Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PGD | P52209 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8373916 | 1.00 | TSHR (0.37) | TSHRTDP1KDM4EPGD | |
| SCHEMBL8155340 | 1.00 | TSHR (0.37) | TSHRTDP1KDM4EPGD | |
| SCHEMBL8160250 | 0.81 | KDM4E (0.31) | TSHRTDP1KDM4E | |
| SCHEMBL8372984 | 0.81 | KDM4E (0.31) | TSHRTDP1KDM4E | |
| SCHEMBL8373921 | 0.81 | KDM4E (0.31) | TSHRTDP1KDM4E | |
| SCHEMBL8816475 | 0.81 | LMNA (0.40) | TSHRTDP1 | |
| SCHEMBL8153450 | 0.78 | LMNA (0.41) | TSHRTDP1PGD | |
| SCHEMBL8156116 | 0.78 | LMNA (0.41) | TSHRTDP1PGD | |
| SCHEMBL8153378 | 0.78 | LMNA (0.41) | TSHRTDP1PGD | |
| SCHEMBL8376318 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0896540-A1 | USE OF PHOSPHONIC ACID ESTERS FOR THE TREATMENT OF FUNCTIONAL DISORDERS OF THE BRAIN AND DEPRESSION | Troponwerke GmbH & Co. KG (DE) | 1999-02-17 | — | — | EP | disclosed |
| WO-1997039756-A1 | USE OF PHOSPHONIC ACID ESTERS FOR THE TREATMENT OF FUNCTIONAL DISORDERS OF THE BRAIN AND DEPRESSION | TROPONWERKE GMBH & CO. KG (DE) | 1997-10-30 | — | — | WO | disclosed |