SCHEMBL8372123

SCHEMBL8372123

CO[C@@H]1O[C@H](COCc2ccccc2)[C@H]2OC(C)(C)O[C@@H]12

nearest known ligand 0.52

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SSTR1 P30872 1/20 0.43
SSTR2 P30874 1/20 0.43
SSTR4 P31391 1/20 0.43
SSTR3 P32745 1/20 0.43
SSTR5 P35346 1/20 0.43
ALDH1A1 P00352 1/20 0.42
GJB2 P29033 1/20 0.40
SLC6A2 P23975 1/20 0.38
NT5E P21589 1/20 0.38
TAAR1 Q96RJ0 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7150309 1.00 SSTR1 (0.43) SSTR1SSTR2SSTR4SSTR3SSTR5
SCHEMBL19682244 1.00 SSTR1 (0.43) SSTR1SSTR2SSTR4SSTR3SSTR5
SCHEMBL29546612 0.93 SSTR1 (0.45) SSTR1SSTR2SSTR4SSTR3SSTR5
SCHEMBL9847478 0.89 SSTR1 (0.52) SSTR1SSTR2SSTR4SSTR3SSTR5
SCHEMBL14304304 0.85 LGALS8 (0.45) SSTR1SSTR2SSTR4SSTR3SSTR5
SCHEMBL13396605 0.85 SSTR1 (0.47) SSTR1SSTR2SSTR4SSTR3SSTR5
SCHEMBL7155640 0.85 SSTR1 (0.47) SSTR1SSTR2SSTR4SSTR3SSTR5
SCHEMBL7150456 0.85 SSTR1 (0.47) SSTR1SSTR2SSTR4SSTR3SSTR5
SCHEMBL3317080 0.85 SSTR1 (0.47) SSTR1SSTR2SSTR4SSTR3SSTR5
SCHEMBL7151060 0.85 SSTR1 (0.47) SSTR1SSTR2SSTR4SSTR3SSTR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0565590-B1 ADHESIN-OLIGOSACCHARIDE CONJUGATE VACCINE FOR $i(HAEMOPHILUS INFLUENZAE) ANTEX BIOLOG INC (US) 1999-03-03 EP disclosed
US-5843463-A Adhesin-oligosaccharide conjugate vaccine for Haemophilus influenzae ANTEXBIOLOGICS, INC. (US) 1998-12-01 US disclosed
US-5721115-A GENETIC ENGINEERING ANTEX BIOLOGICS, INC. (US) 1998-02-24 US disclosed
US-5679547-A COMPLEXING ANTEX BIOLOGICS FORMERLLY MICROCARB INC. (US) 1997-10-21 US disclosed
WO-1994000149-A1 ADHESIN-OLIGOSACCHARIDE CONJUGATE VACCINE FOR $i(HAEMOPHILUS INFLUENZAE) MICROCARB INC. (US) 1994-01-06 WO disclosed