Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.53 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8372576 | 1.00 | ADORA2A (0.53) | ADORA2AADORA2B | |
| SCHEMBL7396871 | 0.88 | KDM4E (0.62) | ADORA2AADORA2B | |
| SCHEMBL7396869 | 0.88 | KDM4E (0.62) | ADORA2AADORA2B | |
| SCHEMBL7722847 | 0.83 | — | — | |
| SCHEMBL7722853 | 0.83 | — | — | |
| SCHEMBL7728633 | 0.82 | ADORA2B (0.55) | ADORA2B | |
| SCHEMBL7728626 | 0.82 | ADORA2B (0.55) | ADORA2B | |
| SCHEMBL8371208 | 0.81 | ADORA2B (0.55) | ADORA2AADORA2B | |
| SCHEMBL8371211 | 0.81 | ADORA2B (0.55) | ADORA2AADORA2B | |
| SCHEMBL6046607 | 0.81 | ADORA2A (0.55) | ADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0559893-B1 | XANTHINE DERIVATIVE | KYOWA HAKKO KOGYO KK (JP) | 1999-02-03 | — | — | EP | disclosed |
| US-5756735-A | ADENOSINE A2 RECEPTOR ANTAGONISTS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1998-05-26 | — | — | US | disclosed |
| EP-0559893-A1 | XANTHINE DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1993-09-15 | — | — | EP | disclosed |