Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.37 |
| ▸ | PSMB5 | P28074 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4103020 | 0.81 | TGFBR1 (0.38) | TGFBR1PSMB5 | |
| SCHEMBL12643180 | 0.81 | MEN1 (0.43) | TGFBR1TSHRMEN1FAAHMAPK1 | |
| SCHEMBL10076774 | 0.79 | MAPK1 (0.42) | TSHRMEN1FAAHMAPK1KMT2A | |
| SCHEMBL8376895 | 0.78 | CYP2D6 (0.43) | TGFBR1TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL7542542 | 0.78 | TGFBR1 (0.36) | TGFBR1 | |
| SCHEMBL1737637 | 0.77 | TGFBR1 (0.34) | TGFBR1MEN1KMT2ARXFP1ALDH1A1 | |
| SCHEMBL25968074 | 0.77 | TGFBR1 (0.35) | TGFBR1ALDH1A1 | |
| SCHEMBL8376801 | 0.77 | TGFBR1 (0.35) | TGFBR1ALDH1A1 | |
| SCHEMBL12333030 | 0.75 | MAPK1 (0.54) | MEN1FAAHMAPK1KMT2AALDH1A1 | |
| SCHEMBL27050 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5883211-A | Thermoreversible hydrogels comprising linear copolymers and their use in electrophoresis | ACLARA BIOSCIENCES, INC. (US) | 1999-03-16 | — | — | US | disclosed |
| WO-1997040078-A1 | THERMOREVERSIBLE HYDROGELS COMPRISING NON-CROSSLINKED COPOLYMERS AND THEIR USE IN ELECTROPHORESIS | SOANE BIOSCIENCES (US) | 1997-10-30 | — | — | WO | disclosed |