SCHEMBL8374045

SCHEMBL8374045

Cl[Cu-](Cl)Cl.N#Cc1ccc(C[P+](c2ccccc2)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.49

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SNCA P37840 2/20 0.49
TSHR P16473 1/20 0.42
MAPT P10636 1/20 0.41
MAOB P27338 5/20 0.41
CCR2 P41597 1/20 0.41
MAOA P21397 4/20 0.40
LOXL2 Q9Y4K0 2/20 0.40
CYP2A6 P11509 1/20 0.40
CYP19A1 P11511 3/20 0.38
CYP11B1 P15538 1/20 0.38
CYP11B2 P19099 1/20 0.38
NPC1 O15118 1/20 0.38
GAA P10253 1/20 0.38
RAB9A P51151 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
CRHBP P24387 1/20 0.38
CRHR2 Q13324 1/20 0.38
HIF1A Q16665 1/20 0.36
KDM1A O60341 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL7341008 0.91 SNCA (0.56) SNCATSHRMAPTMAOBCCR2
Hydrochloric Acid SCHEMBL1575597 0.91 SNCA (0.53) SNCATSHRMAPTMAOBMAOA
SCHEMBL8375898 0.90 SNCA (0.49) SNCATSHRMAPTMAOBCCR2
SCHEMBL8376827 0.90 SNCA (0.49) SNCATSHRMAPTMAOBCCR2
SCHEMBL8604281 0.90 SNCA (0.49) SNCATSHRMAPTMAOBCCR2
SCHEMBL8373311 0.82 SNCA (0.57) SNCATSHRMAOACYP2A6HIF1A
SCHEMBL8376829 0.81 SNCA (0.44) SNCATSHRMAPTMAOBMAOA
SCHEMBL8374368 0.79 SNCA (0.55) SNCATSHRHIF1A
Bromide SCHEMBL11046289 0.78 TSHR (0.58) SNCATSHRMAOBMAOACYP2A6
SCHEMBL8376764 0.77 SNCA (0.53) SNCALOXL2CYP19A1CYP11B1CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0718712-B1 Quaternary phosphonium trihalocuprate salts as charge-control agents for toners and developers EASTMAN KODAK CO (US) 1999-03-10 EP disclosed
US-5547803-A Quaternary phosphonium trihalocuprate salts as charge-control agents for toners and developers EASTMAN KODAK COMPANY (US) 1996-08-20 US disclosed
EP-0718712-A1 Quaternary phosphonium trihalocuprate salts as charge-control agents for toners and developers EASTMAN KODAK COMPANY (US) 1996-06-26 EP disclosed