SCHEMBL8374368

SCHEMBL8374368

Cl[Cu-](Cl)Cl.Clc1ccc(C[P+](c2ccccc2)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SNCA P37840 2/20 0.55
HIF1A Q16665 1/20 0.41
SLC6A4 P31645 1/20 0.41
SIGMAR1 Q99720 1/20 0.40
SLC6A2 P23975 1/20 0.38
SLC6A3 Q01959 1/20 0.38
TSHR P16473 1/20 0.37
CYP1A2 P05177 1/20 0.37
CHRNB2 P17787 1/20 0.37
CHRNA4 P43681 1/20 0.37
CNR1 P21554 1/20 0.36
CNR2 P34972 1/20 0.36
ALDH1A1 P00352 1/20 0.36
CYP3A4 P08684 1/20 0.36
PPARG P37231 4/20 0.36
PPARA Q07869 4/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30596301 0.94 SNCA (0.60) SNCAHIF1ASLC6A4SIGMAR1SLC6A2
Hydrochloric Acid SCHEMBL330374 0.92 SNCA (0.58) SNCAHIF1ASLC6A4SIGMAR1SLC6A2
Bromide SCHEMBL4171166 0.92 SNCA (0.61) SNCAHIF1ASLC6A4SIGMAR1SLC6A2
SCHEMBL8375990 0.89 SNCA (0.55) SNCAHIF1ASLC6A4SIGMAR1SLC6A2
SCHEMBL8603554 0.89 SNCA (0.55) SNCAHIF1ASLC6A4SIGMAR1SLC6A2
SCHEMBL8372338 0.89 SNCA (0.55) SNCAHIF1ASLC6A4SIGMAR1SLC6A2
SCHEMBL8373311 0.88 SNCA (0.57) SNCAHIF1ASLC6A4SIGMAR1SLC6A2
Hydrochloric Acid SCHEMBL2224568 0.84 SNCA (0.48) SNCAHIF1ASLC6A4SIGMAR1TSHR
SCHEMBL8374375 0.83 SNCA (0.53) SNCAHIF1ATSHRALDH1A1CYP3A4
SCHEMBL8376764 0.83 SNCA (0.53) SNCAHIF1AALDH1A1CYP3A4PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0718712-B1 Quaternary phosphonium trihalocuprate salts as charge-control agents for toners and developers EASTMAN KODAK CO (US) 1999-03-10 EP disclosed
US-5547803-A Quaternary phosphonium trihalocuprate salts as charge-control agents for toners and developers EASTMAN KODAK COMPANY (US) 1996-08-20 US disclosed
EP-0718712-A1 Quaternary phosphonium trihalocuprate salts as charge-control agents for toners and developers EASTMAN KODAK COMPANY (US) 1996-06-26 EP disclosed