Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 6/20 | 0.54 |
| ▸ | MEN1 | O00255 | 7/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | CASR | P41180 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | THRA | P10827 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8379789 | 0.92 | CASR (0.51) | ALOX5MEN1KMT2APOLBMAPT | |
| SCHEMBL14920940 | 0.90 | MAPT (0.48) | ALOX5MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL8374111 | 0.89 | CASR (0.46) | ALOX5MEN1KMT2AMAPTCASR | |
| SCHEMBL14934959 | 0.83 | SMN1; SMN2 (0.44) | ALOX5MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL9167111 | 0.82 | ALOX5 (0.75) | ALOX5MEN1KMT2APOLBMAPT | |
| SCHEMBL8377047 | 0.80 | ALOX5 (0.50) | ALOX5MEN1KMT2APOLBMAPT | |
| SCHEMBL19311948 | 0.80 | TSHR (0.49) | ALOX5MEN1KMT2APOLBMAPT | |
| SCHEMBL11582892 | 0.78 | MEN1 (0.70) | ALOX5MEN1KMT2APOLBMAPT | |
| SCHEMBL8380032 | 0.77 | POLB (0.69) | ALOX5MEN1KMT2APOLBMAPT | |
| Hydrochloric Acid SCHEMBL8374390 | 0.77 | SNCA (0.38) | MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5958376-A | Iodinated X-ray contrast media | NYCOMED IMAGING AS (NO) | 1999-09-28 | — | — | US | disclosed |
| US-5958375-A | Urea-linked, iodinated bis phenyl compounds for X-ray contrast media | NYCOMED IMAGING AS (NO) | 1999-09-28 | — | — | US | disclosed |
| EP-0782565-B1 | IODINATED X-RAY-CONTRAST MEDIA | NYCOMED IMAGING AS (NO) | 1999-04-07 | — | — | EP | disclosed |
| EP-0782565-A1 | IODINATED X-RAY-CONTRAST MEDIA | NYCOMED IMAGING AS (NO) | 1997-07-09 | — | — | EP | disclosed |
| WO-1996009285-A1 | IODINATED X-RAY-CONTRAST MEDIA | NYCOMED IMAGING AS (NO) | 1996-03-28 | — | — | WO | disclosed |