Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.71 |
| ▸ | P4HB | P07237 | 6/20 | 0.71 |
| ▸ | AKR1B1 | P15121 | 5/20 | 0.71 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.71 |
| ▸ | MAOA | P21397 | 4/20 | 0.71 |
| ▸ | XDH | P47989 | 4/20 | 0.71 |
| ▸ | SLCO2B1 | O94956 | 3/20 | 0.71 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.71 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.71 |
| ▸ | CA12 | O43570 | 2/20 | 0.71 |
| ▸ | CA2 | P00918 | 2/20 | 0.71 |
| ▸ | CA4 | P22748 | 2/20 | 0.71 |
| ▸ | CA7 | P43166 | 2/20 | 0.71 |
| ▸ | GAA | P10253 | 5/20 | 0.66 |
| ▸ | MAPT | P10636 | 5/20 | 0.66 |
| ▸ | POLB | P06746 | 4/20 | 0.66 |
| ▸ | ALPI | P09923 | 2/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL925803 | 1.00 | KDM4E (0.71) | KDM4EP4HBAKR1B1EPHX2MAOA | |
| SCHEMBL6903921 | 0.93 | NQO2 (0.70) | KDM4EP4HBAKR1B1EPHX2MAOA | |
| SCHEMBL4650695 | 0.89 | KDM4E (0.70) | KDM4EP4HBAKR1B1EPHX2MAOA | |
| SCHEMBL6905094 | 0.88 | MEN1 (0.66) | KDM4EP4HBAKR1B1EPHX2MAOA | |
| SCHEMBL7601750 | 0.86 | KDM4E (0.73) | KDM4EP4HBAKR1B1EPHX2MAOA | |
| SCHEMBL2510346 | 0.86 | KDM4E (0.73) | KDM4EP4HBAKR1B1EPHX2MAOA | |
| SCHEMBL17938818 | 0.86 | KDM4E (0.73) | KDM4EP4HBAKR1B1EPHX2MAOA | |
| SCHEMBL25414144 | 0.86 | P4HB (0.83) | KDM4EP4HBAKR1B1EPHX2MAOA | |
| SCHEMBL21408655 | 0.84 | AKR1B1 (0.74) | KDM4EP4HBAKR1B1EPHX2MAOA | |
| SCHEMBL24608 | 0.84 | AKR1B1 (0.74) | KDM4EP4HBAKR1B1EPHX2MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0900375-A1 | PHARMACEUTICAL GRADE BOTANICAL DRUGS | Pharmaprint, Inc. (US) | 1999-03-10 | — | — | EP | disclosed |
| WO-1997039355-A1 | PHARMACEUTICAL GRADE BOTANICAL DRUGS | PHARMAPRINT, INC. (US) | 1997-10-23 | — | — | WO | disclosed |