SCHEMBL8374252

SCHEMBL8374252

CC[C@](C)(OC1CCCCO1)C(=O)O

nearest known ligand 0.40

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
ADORA3 P0DMS8 1/20 0.37
PPARG P37231 2/20 0.35
PPARA Q07869 2/20 0.35
CREBBP Q92793 1/20 0.32
SLC6A3 Q01959 2/20 0.31
FKBP1A P62942 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29005522 1.00 MEN1 (0.40) MEN1KMT2AADORA3PPARGPPARA
SCHEMBL3618302 0.80 MEN1 (0.38) MEN1KMT2ASLC6A3
SCHEMBL24784170 0.76 MEN1 (0.36) MEN1KMT2ASLC6A3
SCHEMBL16265344 0.75 ALDH1A1 (0.36) MEN1KMT2A
SCHEMBL3609772 0.73 CYP4F2 (0.41) MEN1KMT2APPARAFKBP1A
SCHEMBL29057605 0.73 MEN1 (0.32) MEN1KMT2AFKBP1A
SCHEMBL5570411 0.73 MEN1 (0.40) MEN1KMT2ASLC6A3
SCHEMBL5570408 0.73 MEN1 (0.40) MEN1KMT2ASLC6A3
SCHEMBL10352166 0.73 MEN1 (0.35) MEN1KMT2ASLC6A3
SCHEMBL23779185 0.73 MEN1 (0.35) MEN1KMT2ASLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0897917-A1 Compounds for use in the preparation of antiretroviral enantiomeric nucleotide analogs INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) 1999-02-24 EP disclosed
EP-0728752-A1 Triazole compounds, their production and use TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1996-08-28 EP disclosed
US-5405861-A Fungicides TAKEDA CHEMICAL INDUSTRIES, CO., LTD. (JP) 1995-04-11 US disclosed
EP-0421210-A2 Triazole compounds, their production and use Takeda Chemical Industries, Ltd. (JP) 1991-04-10 EP disclosed