SCHEMBL8374306

SCHEMBL8374306

CCO[Si](CC(C)c1ccccc1)(OCC)OCC

nearest known ligand 0.45

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.45
AOC3 Q16853 2/20 0.41
TRPA1 O75762 4/20 0.41
RIPK1 Q13546 1/20 0.40
MAOA P21397 3/20 0.37
MAOB P27338 3/20 0.37
NISCH Q9Y2I1 3/20 0.37
LMNA P02545 1/20 0.36
LTB4R Q15722 1/20 0.36
LTB4R2 Q9NPC1 1/20 0.36
POLB P06746 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18662196 0.84 HRH1 (0.39) TAAR1LMNAPOLB
SCHEMBL31268212 0.83 TAAR1 (0.44) TAAR1AOC3TRPA1RIPK1MAOA
SCHEMBL27866327 0.80 TAAR1 (0.39) TAAR1LMNAPOLB
SCHEMBL8374293 0.80 TAAR1 (0.48) TAAR1AOC3TRPA1RIPK1MAOA
SCHEMBL1765855 0.79 LMNA (0.53) TAAR1AOC3RIPK1LMNAPOLB
SCHEMBL27849343 0.79 POLB (0.39) TAAR1LMNAPOLB
SCHEMBL28165515 0.79 SCN4A (0.43)
SCHEMBL11845975 0.79 ESR1 (0.33)
SCHEMBL27769945 0.79 TAAR1 (0.38) TAAR1TRPA1LMNAPOLB
SCHEMBL28332139 0.78 SLC6A2 (0.35) LMNAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119081406-A Polyphenylene sulfide composite material for capacitor shell and preparation method thereof 江西聚真科技发展有限公司 2024-12-06 CN claimed
EP-0712901-B1 Flame retardant polycarbonate moulding compositions BAYER AG (DE) 1999-03-10 EP claimed
EP-0712901-A2 Flame retardant polycarbonate moulding compositions BAYER AG (DE) 1996-05-22 EP claimed
CN-119081406-A Polyphenylene sulfide composite material for capacitor shell and preparation method thereof 江西聚真科技发展有限公司 2024-12-06 CN disclosed
EP-0712901-B1 Flame retardant polycarbonate moulding compositions BAYER AG (DE) 1999-03-10 EP disclosed
US-5693697-A Flame-resistant polycarbonate moulding-compositions BAYER AKTIENGESELLSCHAFT (DE) 1997-12-02 US disclosed
EP-0712901-A2 Flame retardant polycarbonate moulding compositions BAYER AG (DE) 1996-05-22 EP disclosed