Hydrochloric Acid

Hydrochloric Acid

SCHEMBL2224568

Clc1ccc([P+](Cc2ccccc2)(c2ccc(Cl)cc2)c2ccc(Cl)cc2)cc1.[Cl-]

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SNCA P37840 2/20 0.48
SIGMAR1 Q99720 1/20 0.42
PPARG P37231 3/20 0.41
PPARA Q07869 3/20 0.41
MAPT P10636 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
TSHR P16473 1/20 0.40
CYP1A2 P05177 2/20 0.39
HIF1A Q16665 1/20 0.39
SLC6A4 P31645 1/20 0.39
CNR2 P34972 1/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
AKT1 P31749 1/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL330374 0.92 SNCA (0.58) SNCASIGMAR1PPARGPPARATSHR
SCHEMBL30596301 0.89 SNCA (0.60) SNCASIGMAR1PPARGPPARATSHR
Bromide SCHEMBL4171166 0.88 SNCA (0.61) SNCASIGMAR1PPARGPPARATSHR
Hydrochloric Acid SCHEMBL494 0.84 SNCA (0.63) SNCASIGMAR1TSHRCYP1A2HIF1A
SCHEMBL8374368 0.84 SNCA (0.55) SNCASIGMAR1PPARGPPARATSHR
SCHEMBL8372338 0.84 SNCA (0.55) SNCASIGMAR1PPARGPPARATSHR
SCHEMBL8375990 0.84 SNCA (0.55) SNCASIGMAR1PPARGPPARATSHR
SCHEMBL8603554 0.84 SNCA (0.55) SNCASIGMAR1PPARGPPARAL3MBTL1
Hydrochloric Acid SCHEMBL28828301 0.82 SNCA (0.61) SNCASIGMAR1TSHRCYP1A2HIF1A
Bromide SCHEMBL8331435 0.82 SNCA (0.64) SNCASIGMAR1TSHRCYP1A2HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12570851-B2 Liquids MILLIKEN INDUSTRIALS LIMITED (GB) 2026-03-10 US disclosed
CN-117165057-A liquid 米利肯工业有限公司 2023-12-05 CN disclosed
CN-112739758-B Liquid 博奇斯催化剂(英国)有限公司 2023-08-11 CN disclosed
US-20220073735-A1 LIQUIDS Borchers Catalyst (UK) Limited (GB) 2022-03-10 US disclosed
EP-3818101-A1 LIQUIDS Borchers Catalyst (UK) Limited (GB) 2021-05-12 EP disclosed
CN-112739758-A Liquid, method for producing the same and use thereof 博奇斯催化剂(英国)有限公司 2021-04-30 CN disclosed
WO-2020008203-A1 LIQUIDS CATEXEL LIMITED (GB) 2020-01-09 WO disclosed
US-9150705-B2 Curing liquids OMG ADDITIVES LIMITED (GB) 2015-10-06 US disclosed
EP-2521750-B1 CURING LIQUIDS OMG UK TECHNOLOGY LTD (GB) 2014-07-02 EP disclosed
US-20130123452-A1 CURING LIQUIDS OMG ADDITIVES LIMITED (UK) 2013-05-16 US disclosed
EP-2521750-A1 CURING LIQUIDS OMG Additives Limited (GB) 2012-11-14 EP disclosed
WO-2011083309-A1 CURING LIQUIDS UNILEVER PLC (GB) 2011-07-14 WO disclosed
EP-2343336-A1 Curing liquids Unilever Plc, A Company Registered In England And Wales under company no. 41424 of Unilever House (GB) 2011-07-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12570851-B2 Liquids SOD1, GPX4, SMARCC1 SNCA 3842/4885SIGMAR1 577/4885PPARG 824/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.