Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | GGPS1 | O95749 | 6/20 | 0.35 |
| ▸ | FDPS | P14324 | 9/20 | 0.34 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.33 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8376366 | 1.00 | TSHR (0.38) | TSHRTHRBGGPS1FDPSSMPD1 | |
| SCHEMBL19582750 | 0.91 | TSHR (0.35) | TSHRTHRBGGPS1FDPSSMPD1 | |
| SCHEMBL4903533 | 0.88 | TSHR (0.30) | TSHRTHRBGGPS1FDPS | |
| SCHEMBL638854 | 0.80 | TSHR (0.42) | TSHRTHRBGGPS1FDPSSMPD1 | |
| SCHEMBL14353459 | 0.79 | TSHR (0.36) | TSHRTHRBGGPS1FDPSSMPD1 | |
| SCHEMBL14353297 | 0.79 | TSHR (0.36) | TSHRTHRBGGPS1FDPSSMPD1 | |
| SCHEMBL7076808 | 0.79 | TSHR (0.36) | TSHRTHRBGGPS1FDPSSMPD1 | |
| SCHEMBL19582792 | 0.79 | TSHR (0.36) | TSHRTHRBGGPS1FDPSSMPD1 | |
| SCHEMBL14353600 | 0.79 | TSHR (0.36) | TSHRTHRBGGPS1FDPSSMPD1 | |
| SCHEMBL14353422 | 0.79 | TSHR (0.36) | TSHRTHRBGGPS1FDPSSMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5986042-A | Cross-linked polymer | MITSUI CHEMICALS, INC. (JP) | 1999-11-16 | — | — | US | disclosed |
| EP-0856539-A1 | Cross-linked polymer | Mitsui Chemicals, Inc. (JP) | 1998-08-05 | — | — | EP | disclosed |