SCHEMBL638854

SCHEMBL638854

CCCCCCCCCCCCCCC(CCCCCCCCCCCCCC)(CCCCCCCCCCCCCC)NCC

nearest known ligand 0.42

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.42
THRB P10828 1/20 0.42
GGPS1 O95749 6/20 0.38
FDPS P14324 9/20 0.37
EPHX1 P07099 1/20 0.36
SMPD1 P17405 2/20 0.35
CES2 O00748 1/20 0.35
LPAR1 Q92633 1/20 0.35
LPAR3 Q9UBY5 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28163966 0.97 TSHR (0.40) TSHRTHRBGGPS1FDPSEPHX1
SCHEMBL7708444 0.95 TSHR (0.38) TSHRTHRBGGPS1FDPSEPHX1
SCHEMBL8499691 0.86 LMNA (0.39) TSHRGGPS1FDPS
SCHEMBL28726715 0.84 TSHR (0.32) TSHR
Propylamine SCHEMBL7723167 0.83 DNM1 (0.41) TSHRTHRBGGPS1FDPSEPHX1
SCHEMBL28189372 0.83 HRH3 (0.37) TSHRGGPS1FDPSSMPD1CES2
SCHEMBL8375305 0.80 TSHR (0.38) TSHRTHRBGGPS1FDPSEPHX1
Hydrochloric Acid SCHEMBL29449809 0.80 EPHX1 (0.44) TSHRTHRBEPHX1
SCHEMBL8376366 0.80 TSHR (0.38) TSHRTHRBGGPS1FDPSEPHX1
Hydrochloric Acid SCHEMBL38660495 0.80 EPHX1 (0.44) TSHRTHRBEPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8119195-B2 Mixture containing quaternary ammonium compound and its use AKZO NOBEL N.V. (NL) 2012-02-21 US disclosed
US-20100267874-A1 MIXTURE CONTAINING QUATERNARY AMMONIUM COMPOUND AND ITS USE AKZO NOBEL N.V. (NL) 2010-10-21 US disclosed