⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2641486 | 0.61 | — | — | |
| SCHEMBL7946672 | 0.56 | — | — | |
| SCHEMBL9715235 | 0.52 | — | — | |
| SCHEMBL3767412 | 0.52 | — | — | |
| SCHEMBL4543148 | 0.51 | — | — | |
| SCHEMBL9887362 | 0.51 | — | — | |
| SCHEMBL9887570 | 0.51 | — | — | |
| SCHEMBL9887102 | 0.51 | — | — | |
| SCHEMBL56056 | 0.51 | — | — | |
| SCHEMBL7335791 | 0.51 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0658342-B1 | Antineoplastic pharmaceutical composition containing a fumagillol derivative and a platinum complex | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1999-03-17 | — | — | EP | disclosed |
| EP-0658342-A1 | Antineoplastic pharmaceutical composition containing a fumagillol derivative | Takeda Chemical Industries, Ltd. (JP) | 1995-06-21 | — | — | EP | disclosed |