Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10914080 | 0.85 | IDO1 (0.53) | IDO1RAB9AAKR1C3HTTHTR2A | |
| SCHEMBL11099610 | 0.83 | IDO1 (0.58) | IDO1RAB9AAKR1C3HTTHTR2A | |
| SCHEMBL37664 | 0.82 | HTR2A (0.62) | IDO1RAB9AAKR1C3HTTHTR2A | |
| SCHEMBL11419632 | 0.81 | IDO1 (0.56) | IDO1RAB9AAKR1C3HTTHTR2A | |
| SCHEMBL6399778 | 0.81 | IDO1 (0.59) | IDO1RAB9AAKR1C3HTTHTR2A | |
| SCHEMBL37665 | 0.81 | AKR1C3 (0.62) | IDO1RAB9AAKR1C3HTTHTR2A | |
| SCHEMBL11419629 | 0.81 | HTR2A (0.54) | IDO1RAB9AAKR1C3HTTHTR2A | |
| SCHEMBL10465292 | 0.80 | MAOB (0.56) | IDO1RAB9AAKR1C3HTTHTR2A | |
| SCHEMBL9387902 | 0.80 | IDO1 (0.54) | IDO1RAB9AAKR1C3HTTHTR2A | |
| SCHEMBL4726351 | 0.80 | IDO1 (0.54) | IDO1RAB9AAKR1C3HTTHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0376218-B1 | Racemization free attachment of amino acids to solid phase | PERSEPTIVE BIOSYSTEMS INC (US) | 1999-02-24 | — | — | EP | claimed |
| US-5371210-A | Reacting alpha anomer enriched 2-deoxy-2,2-difluorocarbo-hydrate with nucleobase | ELI LILLY AND COMPANY (US) | 1994-12-06 | — | — | US | claimed |
| US-5187270-A | Solid phase synthesis of peptides using the reaction product of an N-protected amino acid and a 2,4-dichlorophenyl (4-halo methylphenoxy)acetate; efficiency; purity; kinetics | MILLIPORE CORPORATION (US) | 1993-02-16 | — | — | US | claimed |
| EP-0376218-A2 | Racemization free attachment of amino acids to solid phase | PERSEPTIVE BIOSYSTEMS, INC. (US) | 1990-07-04 | — | — | EP | claimed |
| CN-1681781-A | Novel indoline compound and medicinal use thereof | KYOTO PHARMA IND (JP) | 2005-10-12 | — | — | CN | disclosed |
| EP-0376218-B1 | Racemization free attachment of amino acids to solid phase | PERSEPTIVE BIOSYSTEMS INC (US) | 1999-02-24 | — | — | EP | disclosed |
| US-5187270-A | Solid phase synthesis of peptides using the reaction product of an N-protected amino acid and a 2,4-dichlorophenyl (4-halo methylphenoxy)acetate; efficiency; purity; kinetics | MILLIPORE CORPORATION (US) | 1993-02-16 | — | — | US | disclosed |
| EP-0376218-A2 | Racemization free attachment of amino acids to solid phase | PERSEPTIVE BIOSYSTEMS, INC. (US) | 1990-07-04 | — | — | EP | disclosed |