SCHEMBL37664

SCHEMBL37664

O=C(OCc1ccc([N+](=O)[O-])cc1)OCc1ccc([N+](=O)[O-])cc1

nearest known ligand 0.62

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.62
IDO1 P14902 2/20 0.61
RAB9A P51151 2/20 0.59
AKR1C3 P42330 1/20 0.59
HTT P42858 2/20 0.55
MAOB P27338 1/20 0.54
ALDH1A1 P00352 1/20 0.54
TSHR P16473 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6645015 0.93 RAB9A (0.61) HTR2AIDO1RAB9AAKR1C3HTT
SCHEMBL4725847 0.93 HTR2A (0.59) HTR2AIDO1RAB9AAKR1C3HTT
SCHEMBL1029307 0.93 HTR2A (0.59) HTR2AIDO1RAB9AAKR1C3HTT
SCHEMBL6141153 0.92 HTR2A (0.59) HTR2AIDO1RAB9AAKR1C3HTT
SCHEMBL9208980 0.92 HTR2A (0.56) HTR2AIDO1RAB9AAKR1C3HTT
SCHEMBL10949489 0.92 HTR2A (0.56) HTR2AIDO1RAB9AAKR1C3HTT
SCHEMBL10639376 0.90 HTR2A (0.54) HTR2AIDO1RAB9AAKR1C3HTT
SCHEMBL6778096 0.90 HTR2A (0.54) HTR2AIDO1RAB9AAKR1C3HTT
SCHEMBL7289565 0.90 IDO1 (0.64) HTR2AIDO1RAB9AAKR1C3HTT
SCHEMBL9676749 0.90 HTR2A (0.57) HTR2AIDO1RAB9AAKR1C3HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2233 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260035402-A1 C10-ALKYLENE SUBSTITUTED 13-MEMBERED MACROLIDES AND USES THEREOF ZIKANI THERAPEUTICS INC (US) 2026-02-05 US claimed
CN-119350283-A Prazomycin impurity H and preparation method thereof 上海上药新亚药业有限公司 2025-01-24 CN claimed
US-12060334-B2 3-substituted phenazine derivatives as antimicrobial agents UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2024-08-13 US claimed
US-11634449-B2 Macrolides and methods of their preparation and use PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2023-04-25 US claimed
CN-115611933-A Process for preparing arginase inhibitors and synthetic intermediates thereof 因赛特公司 2023-01-17 CN claimed
EP-3649135-B1 SYNTHESIS OF HALICHONDRINS HARVARD COLLEGE (US) 2022-12-28 EP claimed
US-20220332747-A1 MACROLIDES AND METHODS OF THEIR PREPARATION AND USE PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2022-10-20 US claimed
EP-3291676-B1 MITRAGYNINE ANALOGS AND USES THEREOF MEMORIAL SLOAN KETTERING CANCER CENTER (US) 2022-08-17 EP claimed
US-11241435-B2 Uses of salt-inducible kinase (SIK) inhibitors for treating osteoporosis THE GENERAL HOSPITAL CORPORATION (US) 2022-02-08 US claimed
WO-2022016195-A1 PROCESSES FOR THE PREPARATION OF ARGINASE INHIBITORS AND THEIR SYNTHETIC INTERMEDIATES INCYTE CORPORATION (US) 2022-01-20 WO claimed
WO-2005058246-A2 METHOD FOR PREPARING RADIOLABELED THYMIDINE MOLECULAR TECHNOLOGIES, INC. (US) 2005-06-30 WO claimed
US-20050131224-A1 Method for preparing radiolabeled thymidine CTI PET SYSTEMS, INC. 2005-06-16 US claimed
EP-0889901-B1 PROCESS AND INTERMEDIATES FOR THE SYNTHESIS OF LHRH ANTAGONISTS ABBOTT LAB (US) 2001-09-19 EP claimed
EP-0914334-B1 PROCESS AND INTERMEDIATES FOR THE SYNTHESIS OF LHRH ANTAGONISTS ABBOTT LAB (US) 2001-05-30 EP claimed
EP-0914334-A1 PROCESS AND INTERMEDIATES FOR THE SYNTHESIS OF LHRH ANTAGONISTS Abbott Laboratories (US) 1999-05-12 EP claimed
EP-0889901-A1 PROCESS AND INTERMEDIATES FOR THE SYNTHESIS OF LHRH ANTAGONISTS Abbott Laboratories (US) 1999-01-13 EP claimed
US-5710247-A DEPROTECTING OLIGOPEPTIDE; COUPLING ABBOTT LABORATORIES (US) 1998-01-20 US claimed
US-5710246-A COUPLING OLIGOPEPTIDES; DEPROTECTING ABBOTT LABORATORIES (US) 1998-01-20 US claimed
WO-1997034924-A1 PROCESS AND INTERMEDIATES FOR THE SYNTHESIS OF LHRH ANTAGONISTS ABBOTT LABORATORIES (US) 1997-09-25 WO claimed
WO-1997034923-A1 PROCESS AND INTERMEDIATES FOR THE SYNTHESIS OF LHRH ANTAGONISTS ABBOTT LABORATORIES (US) 1997-09-25 WO claimed