Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.39 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | FABP4 | P15090 | 2/20 | 0.39 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | FABP3 | P05413 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8660014 | 0.80 | ADORA3 (0.51) | RXFP1KDM4EALDH1A1GAAADORA3 | |
| SCHEMBL4413557 | 0.75 | KDM4E (0.48) | KDM4EMAPK1ALDH1A1FABP4FABP5 | |
| SCHEMBL8381530 | 0.74 | ACP1 (0.42) | KDM4EMAPK1ALDH1A1FABP4FABP5 | |
| SCHEMBL26534113 | 0.73 | NPY5R (0.47) | KDM4EMAPK1ALDH1A1 | |
| SCHEMBL4417128 | 0.72 | KDM4E (0.49) | KDM4EMAPK1ALDH1A1FABP4POLB | |
| SCHEMBL10730888 | 0.72 | CSF1R (0.43) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL405341 | 0.71 | KDM4E (0.44) | KDM4EMAPK1ALDH1A1GAAMAPT | |
| SCHEMBL30013869 | 0.71 | KDM4E (0.44) | KDM4EMAPK1ALDH1A1GAAMAPT | |
| SCHEMBL9266044 | 0.69 | KDM4E (0.44) | KDM4EMAPK1ALDH1A1MAPTKMT2A | |
| SCHEMBL3668583 | 0.69 | KDM4E (0.48) | KDM4EMAPK1ALDH1A1ADORA3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5874438-A | A DRUG TREATING BRAIN DISORDERS, DISEASES OF CENTRAL NERVOUS SYSTEM, DEMENTIA, DEPRESSION, MYOTONIC DYSTROPHY, ASTHMA | BAYER AKTIENGESELLSCHAFT (DE) | 1999-02-23 | — | — | US | disclosed |