Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | LCK | P06239 | 1/20 | 0.50 |
| ▸ | FYN | P06241 | 1/20 | 0.50 |
| ▸ | DAO | P14920 | 1/20 | 0.50 |
| ▸ | MME | P08473 | 1/20 | 0.49 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.45 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.41 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8150133 | 0.84 | HDAC1 (0.60) | HDAC1HPGDCA2CA1LCK | |
| SCHEMBL7983464 | 0.83 | HDAC1 (0.51) | HDAC1HPGDCA2CA1LCK | |
| SCHEMBL13753456 | 0.81 | HDAC1 (0.56) | HDAC1HPGDCA2CA1LCK | |
| SCHEMBL11103438 | 0.79 | CA2 (0.71) | CA2CA1NPC1RAB9AKDM4C | |
| SCHEMBL11103451 | 0.79 | CA2 (0.71) | CA2CA1NPC1RAB9AKDM4C | |
| SCHEMBL13754513 | 0.78 | HDAC1 (0.53) | HDAC1HPGDCA2CA1LCK | |
| SCHEMBL2796740 | 0.76 | CA1 (0.62) | HDAC1HPGDCA2CA1RAB9A | |
| SCHEMBL698879 | 0.76 | CA1 (0.62) | HDAC1HPGDCA2CA1RAB9A | |
| SCHEMBL698880 | 0.76 | CA1 (0.62) | HDAC1HPGDCA2CA1RAB9A | |
| SCHEMBL15047908 | 0.76 | HDAC1 (0.50) | HDAC1HPGDCA2CA1LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0511003-B1 | Superactive GRF analogs | LILLY CO ELI (US) | 1999-03-24 | — | — | EP | disclosed |
| EP-0511003-A1 | Superactive GRF analogs | ELI LILLY AND COMPANY (US) | 1992-10-28 | — | — | EP | disclosed |