Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.63 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.63 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.63 |
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.52 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.52 |
| ▸ | PPARG | P37231 | 6/20 | 0.50 |
| ▸ | PPARD | Q03181 | 6/20 | 0.50 |
| ▸ | PPARA | Q07869 | 6/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.50 |
| ▸ | TLR2 | O60603 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | FABP4 | P15090 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrahydrofuran SCHEMBL8379357 | 1.00 | TSHR (0.63) | TSHRLMNANFKB1PMP22GPR84 | |
| Sebacic Acid SCHEMBL27554023 | 1.00 | TSHR (0.63) | TSHRLMNANFKB1PMP22GPR84 | |
| Sebacic Acid SCHEMBL27554024 | 1.00 | TSHR (0.63) | TSHRLMNANFKB1PMP22GPR84 | |
| Tetrahydrofuran SCHEMBL8376671 | 1.00 | TSHR (0.63) | TSHRLMNANFKB1PMP22GPR84 | |
| Tetrahydrofuran SCHEMBL8375061 | 1.00 | TSHR (0.63) | TSHRLMNANFKB1PMP22GPR84 | |
| Tetrahydrofuran SCHEMBL8376666 | 1.00 | TSHR (0.63) | TSHRLMNANFKB1PMP22GPR84 | |
| Adipic Acid SCHEMBL1638937 | 0.97 | LMNA (0.61) | TSHRLMNANFKB1PMP22GPR84 | |
| Adipic Acid SCHEMBL28032942 | 0.97 | LMNA (0.61) | TSHRLMNANFKB1PMP22GPR84 | |
| Adipic Acid SCHEMBL25247249 | 0.89 | LMNA (0.65) | TSHRLMNANFKB1PMP22GPR84 | |
| Adipic Acid SCHEMBL7544486 | 0.89 | LMNA (0.65) | TSHRLMNANFKB1PMP22GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE36359-E | SUCH AS N-(15-CARBOXYPENTADECANOYLOXY)SUCCINIMIDE; USED TO MODIFY PROTEINS TO OBTAIN PROTEIN DERIVATIVES HAVING IMPROVED BIOAVAILABILITY, NO ANTIGENICITY AND CAN BE ADMINISTERED TO ANIMALS | KURARAY CO., LTD. (JP) | 1999-10-26 | — | — | US | disclosed |
| EP-0511600-B1 | Long chain carboxylic acid imide ester | KURARAY CO (JP) | 1999-03-17 | — | — | EP | disclosed |
| US-5414089-A | Useful for modifying enzymes or proteins | KURARAY CO., LTD. (JP) | 1995-05-09 | — | — | US | disclosed |
| US-5336782-A | N-(carboxyalkoyloxy)succinimides; modifiers of proteins and enzymes to prolong their plasma half-lives; nontoxic; antitumor and -carcinogenic agents | KURARAY CO., LTD. (JP) | 1994-08-09 | — | — | US | disclosed |
| EP-0511600-A2 | Long chain carboxylic acid imide ester | KURARAY CO., LTD. (JP) | 1992-11-04 | — | — | EP | disclosed |