Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4278263 | 0.94 | RAB9A (0.50) | MAPK1SMN1; SMN2L3MBTL1RAB9AMEN1 | |
| SCHEMBL11752804 | 0.93 | MAPK1 (0.50) | MAPK1SMN1; SMN2L3MBTL1RAB9AMEN1 | |
| SCHEMBL23476146 | 0.90 | MAPK1 (0.59) | MAPK1SMN1; SMN2L3MBTL1RAB9AMEN1 | |
| SCHEMBL11296446 | 0.89 | RAB9A (0.45) | MAPK1SMN1; SMN2L3MBTL1RAB9AMEN1 | |
| SCHEMBL15456601 | 0.87 | MAPK1 (0.46) | MAPK1SMN1; SMN2L3MBTL1RAB9AMEN1 | |
| SCHEMBL11304940 | 0.87 | MAPK1 (0.48) | MAPK1SMN1; SMN2L3MBTL1RAB9AMEN1 | |
| SCHEMBL4274070 | 0.87 | MAPK1 (0.53) | MAPK1SMN1; SMN2L3MBTL1RAB9AMEN1 | |
| SCHEMBL13700584 | 0.83 | SMN1; SMN2 (0.45) | MAPK1SMN1; SMN2L3MBTL1RAB9AMEN1 | |
| SCHEMBL13599620 | 0.81 | MAPK1 (0.48) | MAPK1SMN1; SMN2L3MBTL1RAB9AMEN1 | |
| SCHEMBL11298898 | 0.81 | MAPK1 (0.48) | MAPK1SMN1; SMN2L3MBTL1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE36359-E | SUCH AS N-(15-CARBOXYPENTADECANOYLOXY)SUCCINIMIDE; USED TO MODIFY PROTEINS TO OBTAIN PROTEIN DERIVATIVES HAVING IMPROVED BIOAVAILABILITY, NO ANTIGENICITY AND CAN BE ADMINISTERED TO ANIMALS | KURARAY CO., LTD. (JP) | 1999-10-26 | — | — | US | claimed |
| US-5414089-A | Useful for modifying enzymes or proteins | KURARAY CO., LTD. (JP) | 1995-05-09 | — | — | US | claimed |
| US-RE36359-E | SUCH AS N-(15-CARBOXYPENTADECANOYLOXY)SUCCINIMIDE; USED TO MODIFY PROTEINS TO OBTAIN PROTEIN DERIVATIVES HAVING IMPROVED BIOAVAILABILITY, NO ANTIGENICITY AND CAN BE ADMINISTERED TO ANIMALS | KURARAY CO., LTD. (JP) | 1999-10-26 | — | — | US | disclosed |
| EP-0511600-B1 | Long chain carboxylic acid imide ester | KURARAY CO (JP) | 1999-03-17 | — | — | EP | disclosed |
| US-5414089-A | Useful for modifying enzymes or proteins | KURARAY CO., LTD. (JP) | 1995-05-09 | — | — | US | disclosed |
| US-5336782-A | N-(carboxyalkoyloxy)succinimides; modifiers of proteins and enzymes to prolong their plasma half-lives; nontoxic; antitumor and -carcinogenic agents | KURARAY CO., LTD. (JP) | 1994-08-09 | — | — | US | disclosed |
| EP-0511600-A2 | Long chain carboxylic acid imide ester | KURARAY CO., LTD. (JP) | 1992-11-04 | — | — | EP | disclosed |