Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | PTGES | O14684 | 1/20 | 0.57 |
| ▸ | FLT1 | P17948 | 1/20 | 0.57 |
| ▸ | FLT4 | P35916 | 1/20 | 0.57 |
| ▸ | KDR | P35968 | 1/20 | 0.57 |
| ▸ | EGFR | P00533 | 5/20 | 0.56 |
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | CA2 | P00918 | 2/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | MMP1 | P03956 | 1/20 | 0.51 |
| ▸ | MMP2 | P08253 | 1/20 | 0.51 |
| ▸ | MMP9 | P14780 | 1/20 | 0.51 |
| ▸ | MMP8 | P22894 | 1/20 | 0.51 |
| ▸ | MMP13 | P45452 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9176266 | 0.90 | PTGS2 (0.78) | PTGS2ALDH1A1PTGESFLT1FLT4 | |
| SCHEMBL12201957 | 0.89 | PTGS2 (0.64) | PTGS2ALDH1A1PTGESFLT1FLT4 | |
| SCHEMBL14384145 | 0.84 | PTGS2 (0.66) | PTGS2ALDH1A1FLT1FLT4KDR | |
| SCHEMBL3396415 | 0.83 | PTGS2 (0.68) | PTGS2ALDH1A1PTGESFLT1FLT4 | |
| SCHEMBL9176789 | 0.83 | FLT1 (0.84) | PTGS2ALDH1A1FLT1FLT4KDR | |
| SCHEMBL23447714 | 0.83 | KMT2A (0.73) | PTGS2ALDH1A1FLT1FLT4KDR | |
| SCHEMBL789891 | 0.83 | FLT1 (0.84) | PTGS2ALDH1A1FLT1FLT4KDR | |
| SCHEMBL5931087 | 0.82 | PTGS2 (0.71) | PTGS2ALDH1A1PTGESFLT1FLT4 | |
| SCHEMBL790393 | 0.82 | PTGS2 (0.67) | PTGS2ALDH1A1PTGESFLT1FLT4 | |
| SCHEMBL12201959 | 0.81 | PTGS2 (0.66) | PTGS2ALDH1A1FLT1FLT4KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0774363-B1 | Thermosensitive recording material | OJI PAPER CO (JP) | 1999-03-17 | — | — | EP | disclosed |
| US-5804528-A | SUPPORTED IMAGE-FORMING LAYER CONTAINING FINE COMPOSITE PARTICLES COMPRISING LEUCO DYE DISSOLVED IN AQUEOUS EMULSION POLYMERIZED POLYUREA OR UREAURETHANE COPOLYMER SOLID MATRIX | OJI PAPER CO., LTD. (JP) | 1998-09-08 | — | — | US | disclosed |
| EP-0774363-A1 | Thermosensitive recording material | OJI PAPER CO., LTD. (JP) | 1997-05-21 | — | — | EP | disclosed |