SCHEMBL8375840

SCHEMBL8375840

COC(=O)CS(=O)(=O)O.[MgH2]

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.46
CA12 O43570 6/20 0.43
CA14 Q9ULX7 5/20 0.43
GAA P10253 2/20 0.42
HSD17B10 Q99714 2/20 0.42
MGAM O43451 1/20 0.42
SI P14410 1/20 0.42
MGAM2 Q2M2H8 1/20 0.42
CA9 Q16790 3/20 0.37
CA2 P00918 3/20 0.37
CA7 P43166 2/20 0.37
KMT2A Q03164 2/20 0.34
TET2 Q6N021 1/20 0.34
MEN1 O00255 1/20 0.34
CA1 P00915 1/20 0.34
KDM4E B2RXH2 2/20 0.33
LMNA P02545 2/20 0.33
FNTA P49354 1/20 0.33
FNTB P49356 1/20 0.33
RECQL P46063 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1123070 0.97
SCHEMBL28212451 0.95 TSHR (0.46) TSHRCA12CA14GAAHSD17B10
SCHEMBL5328813 0.95 TSHR (0.46) TSHRCA12CA14GAAHSD17B10
SCHEMBL29889907 0.95 TSHR (0.46) TSHRCA12CA14GAAHSD17B10
SCHEMBL18775983 0.81 TSHR (0.39) TSHRCA12CA14GAAHSD17B10
SCHEMBL10622350 0.78 TSHR (0.52) TSHRCA12CA14GAAHSD17B10
SCHEMBL1968530 0.76
SCHEMBL10173581 0.75 KMT2A (0.32) TSHRCA12CA14KMT2A
SCHEMBL9479402 0.75 ALDH1A1 (0.35) CA2LMNAALDH1A1ACP1
SCHEMBL27612507 0.75 MGAM (0.55) TSHRCA12CA14GAAHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0547162-B1 PHENOL TERMINATED DIESTER COMPOSITION AND CURABLE COMPOSITIONS CONTAINING SAME EXXON CHEMICAL PATENTS INC (US) 1999-03-03 EP disclosed
US-5334671-A Protective coating EXXON CHEMICAL PATENTS INC. (US) 1994-08-02 US disclosed
US-5326831-A COATINGS EXXON CHEMICAL PATENTS INC. (US) 1994-07-05 US disclosed
EP-0547162-A1 PHENOL TERMINATED DIESTER COMPOSITION AND CURABLE COMPOSITIONS CONTAINING SAME EXXON CHEMICAL PATENTS INC. (US) 1993-06-23 EP disclosed
US-5210155-A Coatings and paints; hardness, high impact strength, corrosion resistance, weatherproof, solvent resistance EXXON CHEMICAL PATENTS INC. (US) 1993-05-11 US disclosed
WO-1992003492-A1 PHENOL TERMINATED DIESTER COMPOSITION AND CURABLE COMPOSITIONS CONTAINING SAME EXXON CHEMICAL PATENTS INC. (US) 1992-03-05 WO disclosed