SCHEMBL8375841

SCHEMBL8375841

CCCCc1ccc(N)c(CCCC)c1

nearest known ligand 0.67

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SKP2 Q13309 1/20 0.67
ATP4A P20648 1/20 0.47
ATP4B P51164 1/20 0.47
TLR8 Q9NR97 7/20 0.44
CA2 P00918 2/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
HTR1A P08908 1/20 0.43
HPGD P15428 2/20 0.42
HTR2A P28223 1/20 0.42
NPC1 O15118 1/20 0.42
MAPK1 P28482 1/20 0.42
HTT P42858 1/20 0.42
RAB9A P51151 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
CA1 P00915 1/20 0.41
ALDH1A1 P00352 1/20 0.40
HSD17B10 Q99714 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20824950 0.94 SKP2 (0.59) SKP2ATP4AATP4BTLR8CA2
SCHEMBL16634449 0.94 SKP2 (0.59) SKP2TLR8CA2HTR1AHTR2A
SCHEMBL30439206 0.92 SKP2 (0.58) SKP2TLR8SMN1; SMN2HTR1AHPGD
SCHEMBL10623217 0.92 SKP2 (0.58) SKP2TLR8SMN1; SMN2HTR1AHPGD
SCHEMBL23092976 0.90 SKP2 (0.65) SKP2ATP4AATP4BTLR8CA2
SCHEMBL3297219 0.90 SKP2 (0.55) SKP2ATP4AATP4BTLR8CA2
SCHEMBL20824963 0.90 SKP2 (0.55) SKP2ATP4AATP4BTLR8CA2
SCHEMBL8096077 0.88 SKP2 (0.53) SKP2ATP4AATP4BTLR8CA2
SCHEMBL8094754 0.88 SKP2 (0.53) SKP2ATP4AATP4BTLR8CA2
SCHEMBL8096212 0.86 SKP2 (0.51) SKP2TLR8CA2SMN1; SMN2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0570006-B1 A silver halide photographic light-sensitive material FUJI PHOTO FILM CO LTD (JP) 1999-03-24 EP disclosed
US-5362617-A Multilayer element of support with color couplers FUJI PHOTO FILM CO., LTD. (JP) 1994-11-08 US disclosed
EP-0570006-A1 A silver halide photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1993-11-18 EP disclosed
US-4985159-A Alkenylated toluenediamines as antioxidants for organic materials AIR PRODUCTS AND CHEMICALS, INC. (US) 1991-01-15 US disclosed
EP-0272651-A2 N-tert-butyl derivatives of toluenediamine and mixtures as antioxidant for organic materials AIR PRODUCTS AND CHEMICALS, INC. (US) 1988-06-29 EP disclosed
EP-0270031-A2 Tertiary butyl derivatives of toluenediamine and mixtures as antioxidant for organic materials AIR PRODUCTS AND CHEMICALS, INC. (US) 1988-06-08 EP disclosed
US-4711737-A FOR HYDROCARBON OILS, RUBBER AIR PRODUCTS AND CHEMICALS, INC. (US) 1987-12-08 US disclosed
US-4693837-A Tertiary butyl derivatives of toluenediamine and mixtures as antioxidant for organic materials AIR PRODUCTS AND CHEMICALS, INC. (US) 1987-09-15 US disclosed
EP-0065720-B1 PROCESS FOR PREPARING HYDROXYPHENYL AMINE DERIVATIVES CASSELLA Aktiengesellschaft (DE) 1985-01-09 EP disclosed
EP-0109624-A2 Process for producing shaped articles made from polyurethane-polyurea which may be cellular BASF Aktiengesellschaft (DE) 1984-05-30 EP disclosed
EP-0065720-A1 Process for preparing hydroxyphenyl amine derivatives CASSELLA Aktiengesellschaft (DE) 1982-12-01 EP disclosed
US-4238617-A FROM HYDRAZINE, AN AMINE AND A NITRILE ROHM AND HAAS COMPANY (US) 1980-12-09 US disclosed