SCHEMBL8375992

SCHEMBL8375992

Clc1ccc(C[P+](c2ccccc2)(c2ccccc2)c2ccccc2)cc1.Clc1ccc(C[P+](c2ccccc2)(c2ccccc2)c2ccccc2)cc1.O=[Mn](=O)(O)Cl.O=[Mn](=O)(O)Cl.O=[Mn](=O)([O-])Cl.O=[Mn](=O)([O-])Cl

nearest known ligand 0.49

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SNCA P37840 2/20 0.49
PPARG P37231 7/20 0.36
PPARA Q07869 7/20 0.36
ACP3 P15309 1/20 0.35
PSMB8 P28062 1/20 0.35
PSMB5 P28074 1/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
MAPT P10636 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
PLAAT3 P53816 2/20 0.35
PLAAT5 Q96KN8 2/20 0.35
PLAAT2 Q9NWW9 2/20 0.35
PLAAT4 Q9UL19 2/20 0.35
ALDH1A1 P00352 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP2D6 P10635 1/20 0.34
TSHR P16473 1/20 0.34
CYP2C19 P33261 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8376007 0.91 SNCA (0.50) SNCAACP3ALDH1A1CYP1A2CYP2D6
SCHEMBL8377225 0.87 SNCA (0.47) SNCAPPARGPPARAPSMB8PSMB5
SCHEMBL30596301 0.83 SNCA (0.60) SNCAPPARGPPARAALDH1A1CYP1A2
SCHEMBL8378627 0.83 SNCA (0.44) SNCAPPARGPPARAACP3TDP1
SCHEMBL8376829 0.83 SNCA (0.44) SNCAL3MBTL1MAPTTSHR
Bromide SCHEMBL4171166 0.82 SNCA (0.61) SNCAPPARGPPARAALDH1A1CYP1A2
Hydrochloric Acid SCHEMBL330374 0.82 SNCA (0.58) SNCAPPARGPPARAALDH1A1CYP1A2
SCHEMBL8375990 0.79 SNCA (0.55) SNCAPPARGPPARAPSMB8PSMB5
SCHEMBL8374368 0.79 SNCA (0.55) SNCAPPARGPPARAALDH1A1CYP1A2
SCHEMBL8603554 0.79 SNCA (0.55) SNCAPPARGPPARAL3MBTL1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0718706-B1 Bis(quaternary phosphonium) tetrahalomanganate salts as charge-control agents EASTMAN KODAK CO (US) 1999-03-17 EP disclosed
EP-0718706-A1 Bis(quaternary phosphonium) tetrahalomanganate salts as charge-control agents EASTMAN KODAK COMPANY (US) 1996-06-26 EP disclosed
US-5512407-A Bis(quaternary phosphonium) tetrahalomanganate salts as charge-control agents EASTMAN KODAK COMPANY (US) 1996-04-30 US disclosed