SCHEMBL8376141

SCHEMBL8376141

O=[Mn](=O)(O)Br.O=[Mn](=O)(O)Br.O=[Mn](=O)([O-])Br.O=[Mn](=O)([O-])Br.OCC[P+](c1ccccc1)(c1ccccc1)c1ccccc1.OCC[P+](c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 1/20 0.47
ALDH1A1 P00352 2/20 0.46
TSHR P16473 2/20 0.46
CYP1A2 P05177 1/20 0.46
CYP2D6 P10635 1/20 0.46
CYP2C19 P33261 1/20 0.46
SNCA P37840 2/20 0.35
PTPN1 P18031 1/20 0.33
GSK3B P49841 1/20 0.33
GAA P10253 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
CES2 O00748 2/20 0.31
CES1 P23141 2/20 0.31
MDM2 Q00987 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8379524 0.85 HIF1A (0.45) HIF1AALDH1A1TSHRCYP1A2CYP2D6
SCHEMBL8375272 0.85 HIF1A (0.45) HIF1AALDH1A1TSHRCYP1A2CYP2D6
SCHEMBL8376834 0.83 HIF1A (0.48) HIF1AALDH1A1TSHRCYP1A2CYP2D6
SCHEMBL8376169 0.83 HIF1A (0.44) HIF1AALDH1A1TSHRCYP1A2CYP2D6
Butyltriphenylphosphonium SCHEMBL8374675 0.82 HIF1A (0.42) HIF1AALDH1A1TSHRCYP1A2CYP2D6
SCHEMBL8374664 0.82 HIF1A (0.42) HIF1AALDH1A1TSHRCYP1A2CYP2D6
SCHEMBL29833529 0.81 HIF1A (0.70) HIF1AALDH1A1TSHRCYP1A2CYP2D6
SCHEMBL8376110 0.81 ALDH1A1 (0.39) HIF1AALDH1A1TSHRCYP1A2CYP2D6
SCHEMBL8379553 0.80 ALDH1A1 (0.40) HIF1AALDH1A1TSHRCYP1A2CYP2D6
Decyltriphenylphosphonium SCHEMBL8378820 0.80 ALDH1A1 (0.40) HIF1AALDH1A1TSHRCYP1A2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0718706-B1 Bis(quaternary phosphonium) tetrahalomanganate salts as charge-control agents EASTMAN KODAK CO (US) 1999-03-17 EP disclosed
EP-0718706-A1 Bis(quaternary phosphonium) tetrahalomanganate salts as charge-control agents EASTMAN KODAK COMPANY (US) 1996-06-26 EP disclosed
US-5512407-A Bis(quaternary phosphonium) tetrahalomanganate salts as charge-control agents EASTMAN KODAK COMPANY (US) 1996-04-30 US disclosed