Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 4/20 | 0.71 |
| ▸ | SRD5A1 | P18405 | 3/20 | 0.71 |
| ▸ | AR | P10275 | 4/20 | 0.69 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | HSD3B1 | P14060 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | THPO | P40225 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8376189 | 1.00 | SRD5A2 (0.71) | SRD5A2SRD5A1ARKCNH2LMNA | |
| SCHEMBL8074134 | 0.91 | SRD5A2 (0.70) | SRD5A2SRD5A1ARKCNH2 | |
| SCHEMBL8074137 | 0.91 | SRD5A2 (0.70) | SRD5A2SRD5A1ARKCNH2 | |
| SCHEMBL9022541 | 0.90 | AR (0.68) | SRD5A2SRD5A1ARKCNH2LMNA | |
| SCHEMBL9022270 | 0.90 | AR (0.68) | SRD5A2SRD5A1ARKCNH2LMNA | |
| SCHEMBL9022263 | 0.90 | AR (0.68) | SRD5A2SRD5A1ARKCNH2LMNA | |
| SCHEMBL9022545 | 0.90 | AR (0.68) | SRD5A2SRD5A1ARKCNH2LMNA | |
| SCHEMBL5212103 | 0.89 | AR (0.67) | SRD5A2SRD5A1ARKCNH2LMNA | |
| SCHEMBL10521077 | 0.85 | AR (0.67) | SRD5A2SRD5A1ARKCNH2LMNA | |
| SCHEMBL7790540 | 0.85 | AR (0.67) | SRD5A2SRD5A1ARKCNH2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0902790-A1 | PROCESS FOR PREPARING STEROIDS HAVING A CARBOXAMIDE SIDE-CHAIN | PHARMACIA & UPJOHN S.p.A. (IT) | 1999-03-24 | — | — | EP | disclosed |
| WO-1997040062-A1 | PROCESS FOR PREPARING STEROIDS HAVING A CARBOXAMIDE SIDE-CHAIN | PHARMACIA & UPJOHN S.P.A. (IT) | 1997-10-30 | — | — | WO | disclosed |