Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1483328 | 0.85 | CYP2D6 (0.54) | CYP2D6ALOX5KMT2AEPHX1TRPM8 | |
| SCHEMBL14749339 | 0.85 | CYP2D6 (0.54) | CYP2D6ALOX5KMT2AEPHX1TRPM8 | |
| SCHEMBL5475337 | 0.85 | CYP2D6 (0.54) | CYP2D6ALOX5KMT2AEPHX1TRPM8 | |
| SCHEMBL31242992 | 0.84 | CYP2D6 (0.64) | CYP2D6ALOX5KMT2AEPHX1LMNA | |
| SCHEMBL21327667 | 0.83 | CYP2D6 (0.52) | CYP2D6ALOX5KMT2AEPHX1TRPM8 | |
| SCHEMBL8444103 | 0.83 | CYP2D6 (0.52) | CYP2D6ALOX5KMT2AEPHX1TRPM8 | |
| SCHEMBL3392489 | 0.83 | CYP2D6 (0.70) | CYP2D6ALOX5KMT2ALMNAHIF1A | |
| SCHEMBL15554269 | 0.83 | CYP2D6 (0.70) | CYP2D6ALOX5KMT2ALMNAHIF1A | |
| SCHEMBL11020073 | 0.82 | CYP2D6 (0.50) | CYP2D6ALOX5KMT2AEPHX1TRPM8 | |
| SCHEMBL7475015 | 0.81 | ALOX5 (0.55) | CYP2D6ALOX5EPHX1TRPM8LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-11246501-A | — | — | None | — | — | JP | disclosed |
| CN-112867705-A | Opioid receptor modulators and products and methods related thereto | 埃皮欧黛公司 | 2021-05-28 | — | — | CN | disclosed |
| JP-H11246501-A | PRODUCTION OF OPTICALLY ACTIVE CARBOXYLIC ACID AMIDES | MITSUI CHEM INC | 1999-09-14 | — | — | JP | disclosed |