Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.50 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.50 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5597364 | 0.85 | TDP1 (0.53) | TDP1GABRA1GABRG2GABRB3MAPT | |
| SCHEMBL1407819 | 0.79 | GABRA1 (0.53) | TDP1GABRA1GABRG2GABRB3MAPT | |
| SCHEMBL1407820 | 0.79 | GABRA1 (0.53) | TDP1GABRA1GABRG2GABRB3MAPT | |
| SCHEMBL1407948 | 0.78 | GABRA1 (0.51) | TDP1GABRA1GABRG2GABRB3MAPT | |
| SCHEMBL8257981 | 0.78 | GABRA1 (0.51) | TDP1GABRA1GABRG2GABRB3MAPT | |
| SCHEMBL1407949 | 0.78 | GABRA1 (0.51) | TDP1GABRA1GABRG2GABRB3MAPT | |
| SCHEMBL295455 | 0.76 | TDP1 (0.44) | TDP1GABRA1GABRG2GABRB3MAPT | |
| SCHEMBL295454 | 0.76 | TDP1 (0.44) | TDP1GABRA1GABRG2GABRB3MAPT | |
| SCHEMBL4460051 | 0.75 | MEN1 (0.51) | TDP1GABRA1GABRG2GABRB3MAPT | |
| SCHEMBL4460115 | 0.75 | GABRA1 (0.49) | TDP1GABRA1GABRG2GABRB3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0897916-A2 | Novel 2-(2'-hydroxyphenyl)benzotriazoles and 2-hydroxybenzophenones as light protectors for polymeric materials | Clariant GmbH (DE) | 1999-02-24 | — | — | EP | disclosed |