Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 17/20 | 1.00 |
| ▸ | PTGS1 | P23219 | 4/20 | 1.00 |
| ▸ | GHSR | Q92847 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7505212 | 0.85 | PTGS2 (0.74) | PTGS2PTGS1GHSR | |
| SCHEMBL8376304 | 0.84 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL8380758 | 0.84 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL8376294 | 0.82 | PTGS2 (1.00) | PTGS2PTGS1GHSR | |
| SCHEMBL7502304 | 0.80 | PTGS2 (0.70) | PTGS2PTGS1 | |
| SCHEMBL7503548 | 0.74 | PTGS2 (0.64) | PTGS2PTGS1 | |
| SCHEMBL3742385 | 0.73 | PTGS2 (0.62) | PTGS2PTGS1 | |
| SCHEMBL2736434 | 0.72 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL8381684 | 0.72 | PTGS2 (0.81) | PTGS2PTGS1 | |
| SCHEMBL7512959 | 0.72 | PTGS2 (0.69) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6002014-A | SELECTIVELY INHIBITING THE ACTION OF COX-2; TREATING INFLAMMATION | JAPAN TOBACCO, INC. (JP) | 1999-12-14 | — | — | US | disclosed |
| US-5945539-A | ENZYME INHIBITOR | JAPAN TOBACCO, INC. (JP) | 1999-08-31 | — | — | US | disclosed |
| EP-0826676-A1 | OXAZOLE DERIVATIVES AND USE THEREOF | Japan Tobacco Inc. (JP) | 1998-03-04 | — | — | EP | disclosed |