Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | CKS1B | P61024 | 1/20 | 0.42 |
| ▸ | SKP1 | P63208 | 1/20 | 0.42 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | SUCNR1 | Q9BXA5 | 3/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8375760 | 0.93 | IDO1 (0.43) | S1PR1IDO1CKS1BSKP1SKP2 | |
| SCHEMBL8377410 | 0.92 | S1PR1 (0.42) | S1PR1IDO1CKS1BSKP1SKP2 | |
| SCHEMBL8376923 | 0.90 | S1PR1 (0.41) | S1PR1IDO1CKS1BSKP1SKP2 | |
| SCHEMBL8378816 | 0.90 | S1PR1 (0.42) | S1PR1IDO1CKS1BSKP1SKP2 | |
| SCHEMBL8380070 | 0.85 | IDO1 (0.45) | S1PR1IDO1CKS1BSKP1SKP2 | |
| SCHEMBL8375518 | 0.85 | GABRA5 (0.46) | S1PR1IDO1CKS1BSKP1SKP2 | |
| SCHEMBL8378840 | 0.85 | GABRA5 (0.43) | S1PR1IDO1CKS1BSKP1SKP2 | |
| SCHEMBL8377401 | 0.84 | IDO1 (0.44) | S1PR1IDO1CKS1BSKP1SKP2 | |
| SCHEMBL8376483 | 0.84 | IDO1 (0.44) | S1PR1IDO1CKS1BSKP1SKP2 | |
| SCHEMBL8380037 | 0.84 | IDO1 (0.44) | S1PR1IDO1CKS1BSKP1SKP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6005116-A | HAVE INHIBITION ACTIVITIES AGAINST TYPE A-MONOAMINE OXIDASE; TREATING OR PREVENTING DEPRESSION, PARKINSON'S DISEASE, ALZEHEIMER'S DEMENTIA, OR CEREBROVASCULAR DEMENTIA | SANKYO COMPANY, LIMITED (JP) | 1999-12-21 | — | — | US | disclosed |
| EP-0885891-A1 | ISOXAZOLE DERIVATIVES | SANKYO COMPANY LIMITED (JP) | 1998-12-23 | — | — | EP | disclosed |