Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | CASP3 | P42574 | 2/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7867949 | 0.88 | MDM2 (0.43) | MDM2KMT2ACASP3PTPN1FABP5 | |
| SCHEMBL12555211 | 0.82 | KMT2A (0.47) | MDM2KMT2ACASP3FABP5MEN1 | |
| SCHEMBL6343752 | 0.82 | KMT2A (0.45) | MDM2KMT2ACASP3PTPN1FABP5 | |
| SCHEMBL19228294 | 0.82 | KMT2A (0.41) | MDM2KMT2ACASP3PTPN1FABP5 | |
| SCHEMBL9730060 | 0.81 | MDM2 (0.47) | MDM2KMT2ACASP3FABP5MEN1 | |
| SCHEMBL7772788 | 0.80 | KMT2A (0.46) | MDM2KMT2ACASP3PTPN1FFAR1 | |
| SCHEMBL13523948 | 0.80 | KMT2A (0.46) | MDM2KMT2ACASP3PTPN1FFAR1 | |
| SCHEMBL29719396 | 0.79 | KMT2A (0.53) | MDM2KMT2ACASP3FFAR4 | |
| SCHEMBL8769212 | 0.79 | KMT2A (0.53) | MDM2KMT2ACASP3FFAR4 | |
| SCHEMBL3367289 | 0.79 | KMT2A (0.45) | MDM2KMT2ACASP3PTPN1FABP5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0677061-B1 | POLYPEPTIDES AND ANTI-HIV AGENTS PREPARED THEREFROM | SEIKAGAKU KOGYO CO LTD (JP) | 1999-03-03 | — | — | EP | disclosed |
| US-5776899-A | Polypeptide and anti-HIV agent prepared therefrom | SEIKAGAKU CORPORATION (JP) | 1998-07-07 | — | — | US | disclosed |
| US-5710128-A | Pharmaceutical compositions of lipopolysaccharide-binding polypeptides | YAMAMOTO, NAOKI (JP) | 1998-01-20 | — | — | US | disclosed |
| US-5571892-A | HAVING A C-TERMINUS; TREATMENT FOR AIDS | SEIKAGAKU KOGYO CO., LTD. (JP) | 1996-11-05 | — | — | US | disclosed |
| EP-0502198-B1 | NOVEL POLYPEPTIDE AND ANTI-HIV DRUG PREPARED THEREFROM | SEIKAGAKU KOGYO CO LTD (JP) | 1995-12-27 | — | — | EP | disclosed |
| EP-0677061-A1 | POLYPEPTIDE AND ANTI-HIV AGENT PREPARED THEREFROM | SEIKAGAKU CORPORATION (JP) | 1995-10-18 | — | — | EP | disclosed |
| US-5449752-A | Viricides against human immunodeficiency virus; microbiocides | SEIKAGAKU KOGYO K.K. (JP) | 1995-09-12 | — | — | US | disclosed |
| WO-1995010534-A1 | POLYPEPTIDE AND ANTI-HIV AGENT PREPARED THEREFROM | SEIKAGAKU CORPORATION (JP) | 1995-04-20 | — | — | WO | disclosed |
| EP-0513613-B1 | Novel polypeptides with affinity to lipopolysaccharides and their uses | SEIKAGAKU KOGYO CO LTD (JP) | 1994-11-09 | — | — | EP | disclosed |
| EP-0331073-B1 | BENZHYDRYLAMINE DERIVATIVES | Chugai Seiyaku Kabushiki Kaisha (JP) | 1993-07-28 | — | — | EP | disclosed |
| EP-0513613-A1 | Novel polypeptides with affinity to lipopolysaccharides and their uses | SEIKAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1992-11-19 | — | — | EP | disclosed |
| WO-1992019645-A1 | A NOVEL POLYPEPTIDE WITH AFFINITY TO LIPOPOLYSACCHARIDES AND THEIR USES | SEIKAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1992-11-12 | — | — | WO | disclosed |
| EP-0502198-A1 | NOVEL POLYPEPTIDE AND ANTI-HIV DRUG PREPARED THEREFROM | SEIKAGAKU KOGYO CO., LTD. (JP) | 1992-09-09 | — | — | EP | disclosed |
| US-5051526-A | Reagents for solid phase synthesis of polypeptides | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1991-09-24 | — | — | US | disclosed |
| US-4965405-A | INTERMEDIATE FOR POLYPEPTIDE SYNTHESIS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1990-10-23 | — | — | US | disclosed |
| EP-0331073-A2 | Benzhydrylamine derivatives | Chugai Seiyaku Kabushiki Kaisha (JP) | 1989-09-06 | — | — | EP | disclosed |