Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 2/20 | 0.47 |
| ▸ | MDM4 | O15151 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | CASP3 | P42574 | 3/20 | 0.42 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12555211 | 0.87 | KMT2A (0.47) | MDM2MDM4TP53CASP3FABP5 | |
| SCHEMBL7867949 | 0.85 | MDM2 (0.43) | MDM2MDM4TP53CASP3FABP5 | |
| SCHEMBL9706968 | 0.82 | KMT2A (0.45) | MDM2MDM4TP53CASP3FABP5 | |
| SCHEMBL4395836 | 0.82 | KMT2A (0.45) | MDM2MDM4TP53CASP3FABP5 | |
| SCHEMBL17192730 | 0.82 | KMT2A (0.45) | MDM2MDM4TP53CASP3FABP5 | |
| SCHEMBL8410923 | 0.82 | KMT2A (0.45) | MDM2MDM4TP53CASP3FABP5 | |
| SCHEMBL12873284 | 0.81 | LMNA (0.46) | MDM2MDM4TP53CASP3FABP5 | |
| SCHEMBL8377363 | 0.81 | MDM2 (0.43) | MDM2CASP3FABP5MEN1KMT2A | |
| SCHEMBL6343752 | 0.81 | KMT2A (0.45) | MDM2MDM4TP53CASP3FABP5 | |
| SCHEMBL1745934 | 0.81 | KMT2A (0.45) | MDM2MDM4TP53CASP3FABP5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5124478-A | ACID-LABILE ANCHOR GROUPS FOR THE SYNTHESIS OF PEPTIDE AMIDES BY A SOLID-PHASE METHOD | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-06-23 | — | — | US | disclosed |