Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 13/20 | 0.36 |
| ▸ | PPARG | P37231 | 13/20 | 0.36 |
| ▸ | PPARD | Q03181 | 13/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8380145 | 0.94 | FAAH (0.34) | PPARAPPARGPPARDS1PR1S1PR3 | |
| SCHEMBL8376210 | 0.93 | FAAH (0.35) | PPARAPPARGPPARDS1PR1S1PR3 | |
| SCHEMBL8375714 | 0.92 | FAAH (0.37) | PPARAPPARGPPARDFAAHMGLL | |
| SCHEMBL8376537 | 0.92 | PPARG (0.30) | PPARAPPARGPPARD | |
| SCHEMBL8377319 | 0.90 | FFAR4 (0.33) | NR1H3 | |
| SCHEMBL8378845 | 0.87 | S1PR1 (0.32) | S1PR1S1PR3 | |
| SCHEMBL8376860 | 0.87 | KDM4E (0.30) | — | |
| SCHEMBL8375765 | 0.86 | — | — | |
| SCHEMBL8375748 | 0.86 | — | — | |
| SCHEMBL8375523 | 0.85 | HRH3 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6005116-A | HAVE INHIBITION ACTIVITIES AGAINST TYPE A-MONOAMINE OXIDASE; TREATING OR PREVENTING DEPRESSION, PARKINSON'S DISEASE, ALZEHEIMER'S DEMENTIA, OR CEREBROVASCULAR DEMENTIA | SANKYO COMPANY, LIMITED (JP) | 1999-12-21 | — | — | US | disclosed |
| EP-0885891-A1 | ISOXAZOLE DERIVATIVES | SANKYO COMPANY LIMITED (JP) | 1998-12-23 | — | — | EP | disclosed |