Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.62 |
| ▸ | HPGD | P15428 | 4/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.52 |
| ▸ | MEN1 | O00255 | 7/20 | 0.52 |
| ▸ | HTT | P42858 | 3/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | METAP1 | P53582 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5640862 | 0.86 | KMT2A (0.63) | ALDH1A1KDM4EHPGDKMT2AMEN1 | |
| SCHEMBL11760978 | 0.82 | HPGD (0.63) | ALDH1A1KDM4EHPGDKMT2AMEN1 | |
| SCHEMBL11762631 | 0.82 | ALDH1A1 (0.43) | ALDH1A1KDM4EHPGDKMT2AMEN1 | |
| SCHEMBL4480344 | 0.82 | KMT2A (0.53) | ALDH1A1KDM4EHPGDKMT2AMEN1 | |
| SCHEMBL11488577 | 0.81 | ALDH1A1 (0.59) | ALDH1A1KDM4EHPGDKMT2AMEN1 | |
| SCHEMBL11758947 | 0.80 | ALDH1A1 (0.41) | ALDH1A1KDM4EHPGDKMT2AMEN1 | |
| SCHEMBL11346578 | 0.80 | MAPK14 (0.43) | ALDH1A1KDM4EHPGDKMT2AMEN1 | |
| SCHEMBL3749553 | 0.78 | ALDH1A1 (1.00) | ALDH1A1KDM4EHPGDKMT2AMEN1 | |
| SCHEMBL11480319 | 0.78 | HPGD (0.41) | ALDH1A1KDM4EHPGDKMT2AMEN1 | |
| SCHEMBL7092813 | 0.77 | KDM4E (0.49) | ALDH1A1KDM4EHPGDHTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6008213-A | A INHIBITOR OF VITRONECTIN RECEPTOR AND FIBRINOGEN RECEPTOR; USEFUL FOR INHIBITING PLATELET AGGREGATION AND OSTEOPOROSIS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-12-28 | — | — | US | disclosed |