Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.40 |
| ▸ | ACE | P12821 | 11/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | ACE2 | Q9BYF1 | 4/20 | 0.36 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.36 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.36 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.36 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL9554342 | 0.85 | DPP4 (0.37) | DPP4ACEF2ACE2OPRM1 | |
| SCHEMBL7270568 | 0.85 | ERAP2 (0.43) | DPP4ACEF2ERAP2ERAP1 | |
| Arginine SCHEMBL7270509 | 0.80 | ERAP2 (0.40) | DPP4ACEACE2ERAP2ERAP1 | |
| Arginine SCHEMBL7264392 | 0.79 | ERAP2 (0.44) | DPP4ACEERAP2ERAP1LNPEP | |
| Arginine SCHEMBL7270329 | 0.79 | EPHA2 (0.40) | DPP4ACEERAP2ERAP1LNPEP | |
| SCHEMBL7263949 | 0.79 | DPP4 (0.40) | DPP4ACEF2ERAP2ERAP1 | |
| Arginine SCHEMBL7264233 | 0.78 | ERAP2 (0.41) | DPP4ACEERAP2ERAP1LNPEP | |
| Arginine SCHEMBL7264440 | 0.78 | ERAP2 (0.41) | DPP4ACEERAP2ERAP1LNPEP | |
| SCHEMBL27492704 | 0.78 | ALDH1A1 (0.37) | — | |
| Arginine SCHEMBL7271463 | 0.77 | ERAP2 (0.40) | DPP4ACEERAP2ERAP1LNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0664786-B1 | ARGININE KETO-AMIDE ENZYME INHIBITORS | CORVAS INT INC (US) | 1999-03-24 | — | — | EP | disclosed |