Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | VNN1 | O95497 | 4/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8376916 | 0.81 | CES2 (0.50) | PARP1ALOX15GAAKMT2ANPC1 | |
| SCHEMBL28785920 | 0.81 | ATM (0.36) | VNN1KMT2ANPC1RAB9APKM | |
| SCHEMBL7949522 | 0.81 | PARP1 (0.47) | PARP1KDM4EGAAKMT2ANPC1 | |
| SCHEMBL6016105 | 0.81 | PBRM1 (0.54) | KDM4EKMT2ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL135361 | 0.79 | KMT2A (0.50) | GAAKMT2ANPC1RAB9APKM | |
| SCHEMBL3173817 | 0.76 | PARP1 (0.68) | PARP1VNN1ALOX15GAANPC1 | |
| SCHEMBL343277 | 0.75 | RECQL (0.53) | ALOX15KDM4EKMT2ANPC1RAB9A | |
| SCHEMBL3444927 | 0.74 | PARP1 (0.65) | PARP1VNN1ALOX15GAANPC1 | |
| SCHEMBL1273234 | 0.74 | — | — | |
| SCHEMBL3421073 | 0.74 | NPC1 (0.63) | KMT2ANPC1RAB9ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5962690-A | HERBICIDES | DOW AGROSCIENCES LLC (US) | 1999-10-05 | — | — | US | disclosed |
| EP-0918755-A1 | 1-ALKYL-4-BENZOYL-5-HYDROXYPYRAZOLE COMPOUNDS AND THEIR USE AS HERBICIDES | Dow AgroSciences LLC (US) | 1999-06-02 | — | — | EP | disclosed |
| US-5824802-A | POSTEMERGENT HERBICIDE FOR CORN, WHEAT, BARLEY, RICE | DOW AGROSCIENCES LLC (US) | 1998-10-20 | — | — | US | disclosed |
| WO-1998042678-A1 | 1-ALKYL-4-BENZOYL-5-HYDROXYPYRAZOLE COMPOUNDS AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 1998-10-01 | — | — | WO | disclosed |