Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | CA12 | O43570 | 1/20 | 0.59 |
| ▸ | CA1 | P00915 | 1/20 | 0.59 |
| ▸ | CA2 | P00918 | 1/20 | 0.59 |
| ▸ | CA7 | P43166 | 1/20 | 0.59 |
| ▸ | CA9 | Q16790 | 1/20 | 0.59 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.53 |
| ▸ | MGLL | Q99685 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12626192 | 0.97 | HPGD (0.63) | HPGDCA12CA1CA2CA7 | |
| SCHEMBL9152022 | 0.85 | CA12 (0.77) | HPGDCA12CA1CA2CA7 | |
| SCHEMBL4724436 | 0.82 | KMT2A (0.75) | HPGDCA12CA1CA2CA7 | |
| SCHEMBL1877246 | 0.82 | KMT2A (0.80) | HPGDCA12CA1CA2CA7 | |
| SCHEMBL4499205 | 0.82 | HPGD (0.86) | HPGDCA12CA1CA2CA7 | |
| SCHEMBL24120195 | 0.82 | HPGD (0.61) | HPGDKMT2AMEN1POLBSMN1; SMN2 | |
| SCHEMBL1590712 | 0.81 | KMT2A (0.83) | HPGDCA12CA1CA2CA7 | |
| SCHEMBL27971693 | 0.81 | CA12 (0.70) | HPGDCA12CA1CA2CA7 | |
| SCHEMBL142197 | 0.80 | CA12 (0.68) | HPGDCA12CA1CA2CA7 | |
| SCHEMBL28866336 | 0.80 | CA12 (0.64) | HPGDCA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5883102-A | Pharmaceutically active compounds | ASTRA PHARMACEUTICALS LIMITED (GB) | 1999-03-16 | — | — | US | disclosed |