Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.77 |
| ▸ | CA1 | P00915 | 1/20 | 0.77 |
| ▸ | CA2 | P00918 | 1/20 | 0.77 |
| ▸ | CA7 | P43166 | 1/20 | 0.77 |
| ▸ | CA9 | Q16790 | 1/20 | 0.77 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.70 |
| ▸ | MEN1 | O00255 | 2/20 | 0.69 |
| ▸ | POLB | P06746 | 1/20 | 0.69 |
| ▸ | NPC1 | O15118 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 2/20 | 0.63 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.62 |
| ▸ | MGLL | Q99685 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | PKM | P14618 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27971693 | 0.95 | CA12 (0.70) | CA12CA1CA2CA7CA9 | |
| SCHEMBL142197 | 0.93 | CA12 (0.68) | CA12CA1CA2CA7CA9 | |
| SCHEMBL1877246 | 0.93 | KMT2A (0.80) | CA12CA1CA2CA7CA9 | |
| SCHEMBL4724436 | 0.93 | KMT2A (0.75) | CA12CA1CA2CA7CA9 | |
| SCHEMBL19313021 | 0.92 | CA12 (0.67) | CA12CA1CA2CA7CA9 | |
| SCHEMBL110101 | 0.92 | ALDH1A1 (0.72) | CA12CA1CA2CA7CA9 | |
| SCHEMBL4002999 | 0.92 | ALDH1A1 (0.75) | CA12CA1CA2CA7CA9 | |
| SCHEMBL1590712 | 0.91 | KMT2A (0.83) | CA12CA1CA2CA7CA9 | |
| SCHEMBL16026508 | 0.90 | ALDH1A1 (0.70) | CA12CA1CA2CA7CA9 | |
| SCHEMBL28866336 | 0.90 | CA12 (0.64) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0402312-B1 | P-substituted propane-phosphinic acid compounds | CIBA GEIGY AG (CH) | 1995-01-25 | — | — | EP | disclosed |
| US-5190934-A | Treatment of cognitive and memory disorders | CIBA-GEIGY CORPORATION (US) | 1993-03-02 | — | — | US | disclosed |
| EP-0402312-A2 | P-substituted propane-phosphinic acid compounds | CIBA-GEIGY AG (CH) | 1990-12-12 | — | — | EP | disclosed |
| US-4407939-A | GELATIN MODIFIED WITH SUCCINIC, PHTHALIC OR TRIMELLITIC ANHYDRIDE POSITIONED BETWEEN | FUJI PHOTO FILM CO., LTD. (JP) | 1983-10-04 | — | — | US | disclosed |
| US-4021245-A | GELATION DERIVATIVE, SILICIC ACID ANHYDRIDE | FUJI PHOTO FILM CO., LTD. (JA) | 1977-05-03 | — | — | US | disclosed |