Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.70 |
| ▸ | NPC1 | O15118 | 8/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.70 |
| ▸ | HPGD | P15428 | 4/20 | 0.70 |
| ▸ | TSHR | P16473 | 6/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 5/20 | 0.65 |
| ▸ | GAA | P10253 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene SCHEMBL8378505 | 0.81 | SMN1; SMN2 (0.52) | RAB9ANPC1SMN1; SMN2HPGDTSHR | |
| SCHEMBL7447522 | 0.75 | NAAA (0.58) | RAB9ANPC1MAPTKMT2APKM | |
| SCHEMBL6946206 | 0.73 | KDM4E (0.65) | SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL4698272 | 0.73 | NPC1 (0.73) | NPC1SMN1; SMN2HPGDTSHRMAPT | |
| SCHEMBL2588611 | 0.73 | SMN1; SMN2 (0.67) | RAB9ANPC1SMN1; SMN2HPGDTSHR | |
| SCHEMBL13681487 | 0.72 | NPC1 (0.66) | RAB9ANPC1SMN1; SMN2HPGDTSHR | |
| SCHEMBL11090078 | 0.72 | NPC1 (0.62) | RAB9ANPC1SMN1; SMN2HPGDTSHR | |
| SCHEMBL794685 | 0.72 | HDAC3 (0.72) | RAB9ANPC1SMN1; SMN2HPGDTSHR | |
| SCHEMBL3886790 | 0.72 | KDM4E (0.59) | SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL14445074 | 0.71 | HPGD (0.38) | RAB9ANPC1SMN1; SMN2HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5883102-A | Pharmaceutically active compounds | ASTRA PHARMACEUTICALS LIMITED (GB) | 1999-03-16 | — | — | US | disclosed |