Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 6/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | ADH1C | P00326 | 1/20 | 0.39 |
| ▸ | ADH1A | P07327 | 1/20 | 0.39 |
| ▸ | ADH4 | P08319 | 1/20 | 0.39 |
| ▸ | GBA1 | P04062 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL290987 | 1.00 | DNM1 (0.50) | DNM1TSHRTHRBCA12CA1 | |
| SCHEMBL8375292 | 1.00 | DNM1 (0.50) | DNM1TSHRTHRBCA12CA1 | |
| SCHEMBL8377127 | 1.00 | DNM1 (0.50) | DNM1TSHRTHRBCA12CA1 | |
| SCHEMBL8375332 | 1.00 | DNM1 (0.50) | DNM1TSHRTHRBCA12CA1 | |
| SCHEMBL8377234 | 1.00 | DNM1 (0.50) | DNM1TSHRTHRBCA12CA1 | |
| SCHEMBL3248571 | 1.00 | DNM1 (0.50) | DNM1TSHRTHRBCA12CA1 | |
| SCHEMBL4392237 | 1.00 | DNM1 (0.50) | DNM1TSHRTHRBCA12CA1 | |
| SCHEMBL8374767 | 1.00 | DNM1 (0.50) | DNM1TSHRTHRBCA12CA1 | |
| SCHEMBL8379911 | 1.00 | DNM1 (0.50) | DNM1TSHRTHRBCA12CA1 | |
| SCHEMBL292544 | 1.00 | DNM1 (0.50) | DNM1TSHRTHRBCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118317944-A | Acyclic lipids and methods of use thereof | 雷纳嘉德医疗管理公司 | 2024-07-09 | — | — | CN | disclosed |
| CN-118234707-A | Cyclic lipids and methods of use thereof | 雷纳嘉德医疗管理公司 | 2024-06-21 | — | — | CN | disclosed |
| US-20240024422-A1 | POLYNUCLEOTIDES ENCODING INTERLEUKIN-12 (IL12) AND USES THEREOF | ARES CAPITAL CORPORATION, AS AGENT | 2024-01-25 | — | — | US | disclosed |
| EP-4186518-A1 | POLYNUCLEOTIDES ENCODING INTERLEUKIN-12 (IL12) AND USES THEREOF | ModernaTX, Inc. (US) | 2023-05-31 | — | — | EP | disclosed |
| US-11571463-B2 | Polynucleotides encoding interleukin-12 (IL12) and uses thereof | MODERNATX, INC. (US) | 2023-02-07 | — | — | US | disclosed |
| US-11311602-B2 | Polynucleotides encoding interleukin-12 (IL12) and uses thereof | MODERNATX, INC. (US) | 2022-04-26 | — | — | US | disclosed |
| US-20210299221-A1 | POLYNUCLEOTIDES ENCODING INTERLEUKIN-12 (IL12) AND USES THEREOF | ARES CAPITAL CORPORATION, AS AGENT | 2021-09-30 | — | — | US | disclosed |
| US-11000573-B2 | Polynucleotides encoding interleukin-12 (IL12) and uses thereof | MODERNATX, INC. (US) | 2021-05-11 | — | — | US | disclosed |
| US-20200376081-A1 | POLYNUCLEOTIDES ENCODING INTERLEUKIN-12 (IL12) AND USES THEREOF | MODERNATX, INC. | 2020-12-03 | — | — | US | disclosed |
| US-10646549-B2 | Polynucleotides encoding interleukin-12 (IL12) and uses thereof | MODERNATX, INC. (US) | 2020-05-12 | — | — | US | disclosed |
| US-20190125839-A1 | POLYNUCLEOTIDES ENCODING INTERLEUKIN-12 (IL12) AND USES THEREOF | ARES CAPITAL CORPORATION, AS AGENT | 2019-05-02 | — | — | US | disclosed |
| EP-3458083-A1 | POLYNUCLEOTIDES ENCODING INTERLEUKIN-12 (IL12) AND USES THEREOF | Modernatx, Inc. (US) | 2019-03-27 | — | — | EP | disclosed |
| WO-2017201350-A1 | POLYNUCLEOTIDES ENCODING INTERLEUKIN-12 (IL12) AND USES THEREOF | MODERNATX, INC. (US) | 2017-11-23 | — | — | WO | disclosed |
| US-5986042-A | Cross-linked polymer | MITSUI CHEMICALS, INC. (JP) | 1999-11-16 | — | — | US | disclosed |
| EP-0856539-A1 | Cross-linked polymer | Mitsui Chemicals, Inc. (JP) | 1998-08-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11571463-B2 | Polynucleotides encoding interleukin-12 (IL12) and uses thereof | IL2, IL15, RBM12 | DNM1 3573/4885TSHR 3940/4885THRB 4329/4885 |
| US-11311602-B2 | Polynucleotides encoding interleukin-12 (IL12) and uses thereof | IL2, IL15, RBM12 | DNM1 3573/4885TSHR 3940/4885THRB 4329/4885 |
| US-20210299221-A1 | POLYNUCLEOTIDES ENCODING INTERLEUKIN-12 (IL12) AND USES THEREOF | IL2, IL15, RBM12 | DNM1 3573/4885TSHR 3940/4885THRB 4329/4885 |
| US-10646549-B2 | Polynucleotides encoding interleukin-12 (IL12) and uses thereof | IL2, IL15, RBM12 | DNM1 3573/4885TSHR 3940/4885THRB 4329/4885 |
| US-20200376081-A1 | POLYNUCLEOTIDES ENCODING INTERLEUKIN-12 (IL12) AND USES THEREOF | IL2, IL15, RBM12 | DNM1 3573/4885TSHR 3940/4885THRB 4329/4885 |
| US-20240024422-A1 | POLYNUCLEOTIDES ENCODING INTERLEUKIN-12 (IL12) AND USES THEREOF | IL2, IL15, RBM12 | DNM1 3573/4885TSHR 3940/4885THRB 4329/4885 |
| US-11000573-B2 | Polynucleotides encoding interleukin-12 (IL12) and uses thereof | IL2, IL15, RBM12 | DNM1 3573/4885TSHR 3940/4885THRB 4329/4885 |
| US-20190125839-A1 | POLYNUCLEOTIDES ENCODING INTERLEUKIN-12 (IL12) AND USES THEREOF | IL2, IL15, RBM12 | DNM1 3573/4885TSHR 3940/4885THRB 4329/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.