SCHEMBL8378607

SCHEMBL8378607

CCC1(C)CS(=O)(=O)c2ccccc2C(c2ccccc2)N1

nearest known ligand 0.65

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SLC10A2 Q12908 20/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12069789 1.00 SLC10A2 (0.65) SLC10A2
SCHEMBL8202053 0.90 SLC10A2 (0.65) SLC10A2
SCHEMBL8377425 0.90 SLC10A2 (0.65) SLC10A2
SCHEMBL8620064 0.88 SLC10A2 (0.57) SLC10A2
SCHEMBL8378689 0.87 SLC10A2 (0.73) SLC10A2
Hydrochloric Acid SCHEMBL8620393 0.87 SLC10A2 (0.56) SLC10A2
SCHEMBL21794181 0.85 SLC10A2 (0.54) SLC10A2
SCHEMBL8203749 0.85 SLC10A2 (0.81) SLC10A2
SCHEMBL9961516 0.85 SLC10A2 (0.55) SLC10A2
SCHEMBL17598376 0.83 SLC10A2 (0.55) SLC10A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0626952-B1 HYPOLIPIDAEMIC BENZOTHIAZEPINE COMPOUNDS WELLCOME FOUND (GB) 1999-04-14 EP disclosed
US-5859240-A REDUCTION OF IMINE GROUP; OXIDATION; SALT FORMATION GLAXO WELLCOME INC. (US) 1999-01-12 US disclosed
US-5663165-A ANTICHOLESTEROL, CARDIOVASCULAR GLAXO WELLCOME INC. (US) 1997-09-02 US disclosed
EP-0626952-A1 HYPOLIPIDAEMIC BENZOTHIAZEPINE COMPOUNDS THE WELLCOME FOUNDATION LIMITED (GB) 1994-12-07 EP disclosed
WO-1993016055-A1 HYPOLIPIDAEMIC BENZOTHIAZEPINE COMPOUNDS THE WELLCOME FOUNDATION LIMITED (GB) 1993-08-19 WO disclosed