SCHEMBL837884

SCHEMBL837884

COC(C)(OC)C(C)(C)O[SiH3]

nearest known ligand 0.35

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL435189 0.69 ALDH1A1 (0.55) ALDH1A1
SCHEMBL838469 0.67
SCHEMBL16610471 0.65
SCHEMBL1230286 0.65
SCHEMBL3250230 0.62 ALDH1A1 (0.46) ALDH1A1
SCHEMBL27723741 0.62 ALDH1A1 (0.38) ALDH1A1
SCHEMBL705894 0.62
SCHEMBL11309541 0.62
SCHEMBL21220120 0.62
SCHEMBL171508 0.60 ALDH1A1 (0.55) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1904415-B1 HYDROPHOBING MINERALS AND FILLER MATERIALS DOW CORNING (US) 2014-03-12 EP disclosed
EP-2625233-A1 BIODEGRADABLE HYDROPHOBIC CELLULOSIC SUBSTRATES AND METHODS FOR THEIR PRODUCTION USING REACTIVE SILANES Dow Corning Corporation (US) 2013-08-14 EP disclosed
US-20130190429-A1 Biodegradable Hydrophobic Cellulosic Substrates And Methods For Their Production Using Reactive Silanes DOW CORNING CORPORATION (US) 2013-07-25 US disclosed
WO-2012047312-A1 BIODEGRADABLE HYDROPHOBIC CELLULOSIC SUBSTRATES AND METHODS FOR THEIR PRODUCTION USING REACTIVE SILANES DOW CORNING CORPORATION (US) 2012-04-12 WO disclosed
US-8142856-B2 Preparing hydrolyzate containing polysiloxanes by hydrolyzing hydrolysable silane or hydrolysable silane mixture in presence of acid hydrolysis catalyst andcombining polysiloxane hydrolyzate with mineral and/or filler and optionally with water and/or a catalyst for condensation of the hydrolyzate DOW CORNING CORPORATION (US) 2012-03-27 US disclosed
US-20080286474-A1 Hydrophobing Minerals and Filler Materials DOW SILICONES CORPORATION 2008-11-20 US disclosed
EP-1904415-A2 HYDROPHOBING MINERALS AND FILLER MATERIALS Dow Corning Corporation (US) 2008-04-02 EP disclosed
WO-2007009935-A2 HYDROPHOBING MINERALS AND FILLER MATERIALS DOW CORNING CORPORATION (US) 2007-01-25 WO disclosed