SCHEMBL8379641

SCHEMBL8379641

Br[Mn-](Br)(Br)Br.Br[Mn-](Br)(Br)Br.O=[N+]([O-])c1ccc(C[P+](c2ccccc2)(c2ccccc2)c2ccccc2)cc1.O=[N+]([O-])c1ccc(C[P+](c2ccccc2)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.47
CYP2C19 P33261 1/20 0.47
PTPRF P10586 1/20 0.46
PTPN2 P17706 1/20 0.46
PTPN1 P18031 1/20 0.46
PTPN11 Q06124 1/20 0.46
SNCA P37840 2/20 0.46
ALDH1A1 P00352 4/20 0.46
LMNA P02545 2/20 0.46
CRHBP P24387 3/20 0.44
CRHR2 Q13324 3/20 0.44
LOXL2 Q9Y4K0 1/20 0.43
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
ANPEP P15144 1/20 0.42
ERAP2 Q6P179 1/20 0.42
ERAP1 Q9NZ08 1/20 0.42
SMN1; SMN2 Q16637 2/20 0.41
MAPT P10636 2/20 0.41
KDM4E B2RXH2 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8374037 0.94 CYP1A2 (0.53) CYP1A2CYP2C19PTPRFPTPN2PTPN1
Hydrochloric Acid SCHEMBL5427779 0.92 CYP1A2 (0.51) CYP1A2CYP2C19PTPRFPTPN2PTPN1
Bromide SCHEMBL722749 0.92 SNCA (0.53) CYP1A2CYP2C19PTPRFPTPN2PTPN1
SCHEMBL8374699 0.91 CYP1A2 (0.47) CYP1A2CYP2C19PTPRFPTPN2PTPN1
SCHEMBL8379642 0.84 SNCA (0.44) CYP1A2CYP2C19PTPRFPTPN2PTPN1
SCHEMBL2085893 0.79 SNCA (0.53) CYP1A2CYP2C19SNCAALDH1A1LMNA
SCHEMBL8375275 0.79 SNCA (0.57) CYP1A2CYP2C19SNCAALDH1A1ANPEP
Bromide SCHEMBL5828742 0.78 LMNA (0.44) CYP1A2CYP2C19PTPRFPTPN2PTPN1
SCHEMBL8374035 0.77 SNCA (0.56) CYP1A2CYP2C19SNCAALDH1A1MEN1
SCHEMBL8376876 0.76 SNCA (0.55) SNCAALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0718706-B1 Bis(quaternary phosphonium) tetrahalomanganate salts as charge-control agents EASTMAN KODAK CO (US) 1999-03-17 EP disclosed
EP-0718706-A1 Bis(quaternary phosphonium) tetrahalomanganate salts as charge-control agents EASTMAN KODAK COMPANY (US) 1996-06-26 EP disclosed
US-5512407-A Bis(quaternary phosphonium) tetrahalomanganate salts as charge-control agents EASTMAN KODAK COMPANY (US) 1996-04-30 US disclosed