Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 3/20 | 0.39 |
| ▸ | PPARA | Q07869 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8379704 | 1.00 | MAPT (0.43) | MAPTALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8377860 | 0.87 | HDAC8 (0.45) | ALDH1A1HDAC8ITGB3ITGA2BPPARG | |
| SCHEMBL8379594 | 0.87 | HDAC8 (0.45) | ALDH1A1HDAC8ITGB3ITGA2BPPARG | |
| Hydrochloric Acid SCHEMBL8548666 | 0.82 | ITGB3 (0.44) | MAPTGAANPSR1POLBLMNA | |
| Hydrochloric Acid SCHEMBL8643136 | 0.82 | ITGB3 (0.44) | MAPTGAANPSR1POLBLMNA | |
| Hydrochloric Acid SCHEMBL8548668 | 0.80 | PTPN12 (0.40) | MAPTGAANPSR1POLBLMNA | |
| SCHEMBL8377862 | 0.80 | PPARA (0.45) | MAPTALDH1A1ITGB3ITGA2BHSD17B10 | |
| SCHEMBL31321452 | 0.79 | HDAC8 (0.54) | ALDH1A1CYP1A2CYP2C9CYP2C19HTT | |
| SCHEMBL31725906 | 0.78 | ITGB3 (0.64) | HDAC8ITGB3ITGA2BPPARGPPARA | |
| SCHEMBL8377865 | 0.78 | PPARA (0.41) | MAPTALDH1A1ITGB3ITGA2BPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5973188-A | Acetic acid derivatives | HOFFMANN-LA ROCHE INC. (US) | 1999-10-26 | — | — | US | disclosed |