Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CCR6 | P51684 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8379979 | 1.00 | HTT (0.48) | HTTTP53MAPTALDH1A1KMT2A | |
| SCHEMBL8378021 | 0.88 | SMN1; SMN2 (0.47) | HTTTP53MAPTALDH1A1KMT2A | |
| SCHEMBL8378025 | 0.88 | SMN1; SMN2 (0.47) | HTTTP53MAPTALDH1A1KMT2A | |
| SCHEMBL8375712 | 0.82 | ALDH1A1 (0.50) | HTTTP53MAPTALDH1A1KMT2A | |
| SCHEMBL8375715 | 0.82 | ALDH1A1 (0.50) | HTTTP53MAPTALDH1A1KMT2A | |
| SCHEMBL8441772 | 0.76 | TSHR (0.46) | MAPTALDH1A1KMT2AMEN1HSP90AA1 | |
| SCHEMBL8441775 | 0.76 | TSHR (0.46) | MAPTALDH1A1KMT2AMEN1HSP90AA1 | |
| SCHEMBL27726140 | 0.76 | HTT (0.51) | HTTTP53MAPTALDH1A1KMT2A | |
| SCHEMBL7116626 | 0.75 | SMN1; SMN2 (0.64) | HTTTP53MAPTALDH1A1KMT2A | |
| SCHEMBL15850863 | 0.73 | MAPT (0.53) | MAPTALDH1A1KMT2AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5973189-A | Monoesters of carboxymethylene anthranilic acids and process for preparing the same | CLARIANT GMBH (DE) | 1999-10-26 | — | — | US | disclosed |
| EP-0847382-A1 | MONOESTERS OF CARBOXYMETHYLENE ANTHRANILIC ACIDS AND PROCESS FOR PREPARING THE SAME | Clariant GmbH (DE) | 1998-06-17 | — | — | EP | disclosed |
| WO-1997008131-A1 | MONOESTERS OF CARBOXYMETHYLENE ANTHRANILIC ACIDS AND PROCESS FOR PREPARING THE SAME | CLARIANT GMBH (DE) | 1997-03-06 | — | — | WO | disclosed |