Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.30 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10952198 | 0.80 | — | — | |
| SCHEMBL3083581 | 0.78 | — | — | |
| SCHEMBL9425850 | 0.75 | CRBN (0.45) | CRBNTSHRNFKB1LMNACYP1A2 | |
| SCHEMBL3086052 | 0.74 | CRBN (0.40) | CRBNMAPTCACNA1BAPBA1 | |
| SCHEMBL767374 | 0.73 | — | — | |
| SCHEMBL376341 | 0.73 | — | — | |
| SCHEMBL8672962 | 0.73 | — | — | |
| SCHEMBL3065583 | 0.72 | CRBN (0.39) | CRBN | |
| SCHEMBL23002881 | 0.71 | — | — | |
| SCHEMBL16143868 | 0.71 | CRBN (0.41) | CRBNTSHRNFKB1LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108026237-A | The bicomponent polyurethane coating of damage resistant | 科思创德国股份有限公司 | 2018-05-11 | — | — | CN | claimed |
| CN-106459339-A | Polyisocyanates having thioallophanate structure | 科思创德国股份有限公司 | 2017-02-22 | — | — | CN | claimed |
| CN-106414540-A | Thiourohurethanate polyisocyanates containing silane groups | 科思创德国股份有限公司 | 2017-02-15 | — | — | CN | claimed |
| CN-109890865-A | Production of plastics by catalytic crosslinking of blocked polyisocyanates | 科思创德国股份有限公司 | 2019-06-14 | — | — | CN | disclosed |
| CN-109843961-A | The method and equipment for coating of coil and stsip of blocked polyisocyanate containing catalytic crosslinking | 科思创德国股份有限公司 | 2019-06-04 | — | — | CN | disclosed |
| CN-109715691-A | Anisotropic composite material based on polyisocyanates | 科思创德国股份有限公司 | 2019-05-03 | — | — | CN | disclosed |
| CN-109071762-A | Polyisocyanurate plastic containing siloxane group and method for producing same | 科思创德国股份有限公司 | 2018-12-21 | — | — | CN | disclosed |
| CN-108026237-A | The bicomponent polyurethane coating of damage resistant | 科思创德国股份有限公司 | 2018-05-11 | — | — | CN | disclosed |
| CN-108026237-A | The bicomponent polyurethane coating of damage resistant | 科思创德国股份有限公司 | 2018-05-11 | — | — | CN | disclosed |
| CN-106459339-A | Polyisocyanates having thioallophanate structure | 科思创德国股份有限公司 | 2017-02-22 | — | — | CN | disclosed |
| CN-106414540-A | Thiourohurethanate polyisocyanates containing silane groups | 科思创德国股份有限公司 | 2017-02-15 | — | — | CN | disclosed |
| US-5889068-A | REACTION PRODUCT OF AN ISOCYANATE COMPRISING, A STABLE, LIQUID METHYLENEDIPHENYL DIISOCYANATE BASED PREPOLYMER CONTAINING ALLOPHANATE MODIFIED METHYELENDIPHENYL DIISOCYANATE WITH POLYOL AND A BLOWING AGENT | BAYER CORPORATION (US) | 1999-03-30 | — | — | US | disclosed |