Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | LSS | P48449 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8380286 | 1.00 | HTR3A (0.41) | HTR3ASLC18A3DRD2SLC2A1NPC1 | |
| SCHEMBL8040826 | 0.95 | SLC18A3 (0.38) | HTR3ASLC18A3DRD2SLC2A1NPC1 | |
| SCHEMBL19502447 | 0.94 | HTR3A (0.44) | HTR3ASLC18A3DRD2SLC2A1MEN1 | |
| SCHEMBL9177545 | 0.89 | HTR3A (0.41) | HTR3ASLC18A3DRD2SLC2A1MEN1 | |
| SCHEMBL9177543 | 0.89 | HTR3A (0.41) | HTR3ASLC18A3DRD2SLC2A1MEN1 | |
| SCHEMBL9177537 | 0.89 | HTR3A (0.41) | HTR3ASLC18A3DRD2SLC2A1MEN1 | |
| SCHEMBL8518604 | 0.85 | ESR2 (0.42) | HTR3ASLC18A3DRD2SLC2A1MEN1 | |
| SCHEMBL8518607 | 0.85 | ESR2 (0.42) | HTR3ASLC18A3DRD2SLC2A1MEN1 | |
| SCHEMBL8518611 | 0.85 | ESR2 (0.42) | HTR3ASLC18A3DRD2SLC2A1MEN1 | |
| SCHEMBL18533598 | 0.84 | HTR3A (0.52) | HTR3ASLC18A3DRD2SLC2A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0475273-B1 | Liquid crystal mixture containing halogenated alcenyl compounds | MERCK PATENT GMBH (DE) | 1999-04-07 | — | — | EP | disclosed |
| US-5292452-A | Electrooptical devices; high dielectric anisotropy, low rotation viscosity, short response time | HOFFMANN-LA ROCHE INC. (US) | 1994-03-08 | — | — | US | disclosed |
| EP-0475273-A1 | Halogenated alcenyl compounds | F. HOFFMANN-LA ROCHE AG (CH) | 1992-03-18 | — | — | EP | disclosed |