SCHEMBL8380595

SCHEMBL8380595

c1ccc2c(c1)ccc[n+]2-c1ccncc1

nearest known ligand 0.40

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ACHE P22303 13/20 0.40
BCHE P06276 12/20 0.40
MAPT P10636 1/20 0.38
HTT P42858 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5143924 0.85 MAPT (0.50) ACHEBCHEMAPTHTTSMN1; SMN2
SCHEMBL4639895 0.83 MAPT (0.47) ACHEBCHEMAPTHTTSMN1; SMN2
SCHEMBL30384292 0.83 MAPT (0.47) ACHEBCHEMAPTHTTSMN1; SMN2
SCHEMBL5875226 0.82 ACHE (0.39) ACHEBCHE
Iodide SCHEMBL8840974 0.81 MAPT (0.46) ACHEBCHEMAPTHTTSMN1; SMN2
Bromide SCHEMBL27074264 0.81 MAPT (0.46) ACHEBCHEMAPTHTTSMN1; SMN2
SCHEMBL28356391 0.76 KMT2A (0.44) ACHEBCHE
SCHEMBL16470228 0.72 ACHE (0.37) ACHEBCHEMAPTHTTSMN1; SMN2
SCHEMBL29404412 0.72 ACHE (0.37) ACHEBCHEMAPTHTTSMN1; SMN2
SCHEMBL29405292 0.72 TSHR (0.40) ACHEBCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0585745-B1 Direct positive silver halide photographic material and method for forming high contrast positive image using the same DAINIPPON INK & CHEMICALS (JP) 1999-03-24 EP disclosed
US-5362621-A Compound containing pyridine and pyridinium nucleus, reductone developer DAINIPPON INK AND CHEMICALS, INC. (JP) 1994-11-08 US disclosed
EP-0585745-A2 Direct positive silver halide photographic material and method for forming high contrast positive image using the same DAINIPPON INK AND CHEMICALS, INC. (JP) 1994-03-09 EP disclosed