SCHEMBL8380680

SCHEMBL8380680

CC(=O)N1CCCCCCCCC1=O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.50
MITF O75030 1/20 0.50
LMNA P02545 1/20 0.50
NOTUM Q6P988 2/20 0.42
KDM4E B2RXH2 4/20 0.41
MAPT P10636 2/20 0.41
KMT2A Q03164 2/20 0.41
CYP2D6 P10635 2/20 0.41
CYP2C9 P11712 2/20 0.41
RECQL P46063 2/20 0.41
MEN1 O00255 1/20 0.41
CYP1A2 P05177 1/20 0.41
THRB P10828 1/20 0.41
CYP2C19 P33261 1/20 0.41
BLM P54132 1/20 0.41
TP53 P04637 2/20 0.40
ALDH1A1 P00352 2/20 0.40
STAT6 P42226 1/20 0.40
HSD17B10 Q99714 1/20 0.40
BRD4 O60885 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18566 1.00 SMN1; SMN2 (0.50) SMN1; SMN2MITFLMNANOTUMKDM4E
SCHEMBL15071000 1.00 SMN1; SMN2 (0.50) SMN1; SMN2MITFLMNANOTUMKDM4E
SCHEMBL30307790 1.00 SMN1; SMN2 (0.50) SMN1; SMN2MITFLMNANOTUMKDM4E
SCHEMBL15061896 1.00 SMN1; SMN2 (0.50) SMN1; SMN2MITFLMNANOTUMKDM4E
SCHEMBL8379280 1.00 SMN1; SMN2 (0.50) SMN1; SMN2MITFLMNANOTUMKDM4E
SCHEMBL15061890 1.00 SMN1; SMN2 (0.50) SMN1; SMN2MITFLMNANOTUMKDM4E
SCHEMBL15061902 1.00 SMN1; SMN2 (0.50) SMN1; SMN2MITFLMNANOTUMKDM4E
SCHEMBL8382041 1.00 SMN1; SMN2 (0.50) SMN1; SMN2MITFLMNANOTUMKDM4E
SCHEMBL641600 0.98 LMNA (0.52) SMN1; SMN2MITFLMNANOTUMKDM4E
SCHEMBL185461 0.91

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11685818-B2 Fibers treated with polymerization compounds and fiber reinforced composites made therefrom JOHNS MANVILLE (US) 2023-06-27 US disclosed
EP-2607061-B1 Methods of making prepregs JOHNS MANVILLE (US) 2021-05-12 EP disclosed
US-10954349-B2 Fiber reinforced composites made with coupling-activator treated fibers and activator containing reactive resin JOHNS MANVILLE (US) 2021-03-23 US disclosed
US-20200299487-A1 FIBERS TREATED WITH POLYMERIZATION COMPOUNDS AND FIBER REINFORCED COMPOSITES MADE THEREFROM JOHNS MANVILLE 2020-09-24 US disclosed
US-10669402-B2 Fibers treated with polymerization compounds and fiber reinforced composites made therefrom JOHNS MANVILLE (US) 2020-06-02 US disclosed
US-20190284352-A1 FIBER REINFORCED COMPOSITES MADE WITH COUPLING-ACTIVATOR TREATED FIBERS AND ACTIVATOR CONTAINING REACTIVE RESIN JOHNS MANVILLE 2019-09-19 US disclosed
EP-2607400-B1 METHOD OF SIZING AND METHOD OF MAKING A REINFORCED THERMOPLASTIC COMPOSITE JOHNS MANVILLE (US) 2018-05-16 EP disclosed
US-9387626-B2 Fiber reinforced composites made with coupling-activator treated fibers and activator containing reactive resin Manville, Johns (US) 2016-07-12 US disclosed
US-9068101-B2 Sizing compositions and sized products for thermoplastic composites JOHNS MANVILLE (US) 2015-06-30 US disclosed
US-8962735-B2 Methods of making reactive fiber/flake prepregs and reactive prepregs JOHNS MANVILLE (US) 2015-02-24 US disclosed
US-20140296377-A1 SIZING COMPOSITIONS AND SIZED PRODUCTS FOR THERMOPLASTIC COMPOSITES JOHNS MANVILLE 2014-10-02 US disclosed
US-20140256201-A1 FIBER REINFORCED COMPOSITES MADE WITH COUPLING-ACTIVATOR TREATED FIBERS AND ACTIVATOR CONTAINING REACTIVE RESIN JOHNS MANVILLE (US) 2014-09-11 US disclosed
US-8791203-B2 Sizing compositions and sized products for thermoplastic composites JOHNS MANVILLE (US) 2014-07-29 US disclosed
US-20130165585-A1 METHODS OF MAKING REACTIVE FIBER/FLAKE PREPREGS AND REACTIVE PREPREGS JOHNS MANVILLE 2013-06-27 US disclosed
US-20130165548-A1 SIZING COMPOSITIONS AND SIZED PRODUCTS FOR THERMOPLASTIC COMPOSITES JOHNS MANVILLE 2013-06-27 US disclosed
EP-0739880-B1 Process for the preparation of amido peroxycarboxylic acids CLARIANT GMBH (DE) 1999-03-31 EP disclosed
US-5648521-A DECYCLIZATION, OXIDATION HOECHST AKTIENGESELLSCHAFT (DE) 1997-07-15 US disclosed
EP-0739880-A2 Process for the preparation of amido peroxycarboxylic acids HOECHST AKTIENGESELLSCHAFT (DE) 1996-10-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10669402-B2 Fibers treated with polymerization compounds and fiber reinforced composites made therefrom NEFM, VCL, SAMM50 SMN1; SMN2 202/4885MITF 2128/4885LMNA 174/4885
US-20200299487-A1 FIBERS TREATED WITH POLYMERIZATION COMPOUNDS AND FIBER REINFORCED COMPOSITES MADE THEREFROM NEFM, VCL, SAMM50 SMN1; SMN2 202/4885MITF 2128/4885LMNA 174/4885
US-11685818-B2 Fibers treated with polymerization compounds and fiber reinforced composites made therefrom NEFM, VCL, SAMM50 SMN1; SMN2 202/4885MITF 2128/4885LMNA 174/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.