⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28022999 | 0.78 | — | — | |
| SCHEMBL28023003 | 0.78 | — | — | |
| SCHEMBL1027169 | 0.78 | — | — | |
| SCHEMBL8955959 | 0.77 | ALDH1A1 (0.37) | — | |
| SCHEMBL14795082 | 0.76 | HMGCR (0.31) | — | |
| SCHEMBL28114562 | 0.76 | — | — | |
| SCHEMBL13792298 | 0.76 | — | — | |
| SCHEMBL16058445 | 0.74 | — | — | |
| SCHEMBL468215 | 0.74 | — | — | |
| SCHEMBL993024 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106085993-B | It is a kind of from the amidase of grapevine Burkholderia, gene, bacterial strain and its application | 浙江工业大学 | 2019-07-26 | — | — | CN | claimed |
| CN-101945859-B | Bis-(sulfonylamino) derivatives in therapy | ASTRAZENECA AB | 2014-04-09 | — | — | CN | claimed |
| CN-1215434-A | Enzymatic process stereoselective preparation of therapeutic amides | ZENECA LTD (GB) | 1999-04-28 | — | — | CN | claimed |
| CN-106085993-B | It is a kind of from the amidase of grapevine Burkholderia, gene, bacterial strain and its application | 浙江工业大学 | 2019-07-26 | — | — | CN | disclosed |
| CN-106460038-A | Systems and methods for identifying cancers having activated progesterone receptors | 悉尼大学 | 2017-02-22 | — | — | CN | disclosed |
| CN-103354733-B | Use of remote ischemic conditioning for traumatic injury | 儿童医院 | 2017-02-22 | — | — | CN | disclosed |
| CN-106170701-A | For identifying the system and method for progesterone receptor hypotype | 阿尔诺治疗公司 | 2016-11-30 | — | — | CN | disclosed |
| CN-106085993-A | A kind of derive from the amidase of vine Burkholderia, gene, bacterial strain and application thereof | 浙江工业大学 | 2016-11-09 | — | — | CN | disclosed |
| CN-105579045-A | A method for organ arrest, protection and preservation and reducing tissue injury | HTS THERAPEUTICS PTY LTD | 2016-05-11 | — | — | CN | disclosed |
| CN-103951584-B | Derivative of 3-chloro-N-phenyl-4-(the fluoro-2-methyl of 3,3,3-tri--2-hydroxypropanamide base) benzamide and preparation method thereof and application | TSINGHUA UNIVERSITY (CN) | 2016-02-10 | — | — | CN | disclosed |
| CN-103354733-A | Use of remote ischemic conditioning for traumatic injury | HOSPITAL FOR SICK CHILDREN | 2013-10-16 | — | — | CN | disclosed |
| CN-1230178-C | Therapeutic agent for bladder irritation symptom associated with prostatic hyperplasia | KYOWA HAKKO KOGYO KK (JP) | 2005-12-07 | — | — | CN | disclosed |
| CN-1499974-A | Therapeutic agent for bladder irritation symptom associated with prostatic hyperplasia | Э�ͷ���ҵ��ʽ���� | 2004-05-26 | — | — | CN | disclosed |
| CN-1293666-A | Phenylthioamide derivatives and their use as pharmaceuticals | ASTRA ZENECA LTD (SE) | 2001-05-02 | — | — | CN | disclosed |
| CN-1215434-A | Enzymatic process stereoselective preparation of therapeutic amides | ZENECA LTD (GB) | 1999-04-28 | — | — | CN | disclosed |
| EP-0904400-A2 | ENZYMATIC PROCESS FOR STEREOSELECTIVE PREPARATION OF THERAPEUTIC AMIDES | AstraZeneca AB (SE) | 1999-03-31 | — | — | EP | disclosed |
| CN-1038413-C | Therapeutic amides | ZENECA LTD (GB) | 1998-05-20 | — | — | CN | disclosed |
| WO-1997038124-A2 | ENZYMATIC PROCESS FOR STEREOSELECTIVE PREPARATION OF THERAPEUTIC AMIDES | ZENECA LIMITED (GB) | 1997-10-16 | — | — | WO | disclosed |
| CN-1132204-A | Novel heterocyclic amides | HAFSLUND NYCOMED PHARMA (AT) | 1996-10-02 | — | — | CN | disclosed |
| CN-1069727-A | The acid amides that is used for the treatment of | ICI PLC (GB) | 1993-03-10 | — | — | CN | disclosed |